SCHEMBL6548792

SCHEMBL6548792

Cc1ccc(C(=O)P(=O)(C(=O)c2ccc(C)cc2C)c2ccccc2)c(C)c1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 1/20 0.53
KMT2A Q03164 4/20 0.48
RAB9A P51151 4/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
NPC1 O15118 3/20 0.47
HSD11B1 P28845 1/20 0.47
AVPR2 P30518 1/20 0.46
GPR27 Q9NS67 1/20 0.46
HDAC7 Q8WUI4 1/20 0.43
HTT P42858 2/20 0.42
MEN1 O00255 2/20 0.42
POLB P06746 1/20 0.41
KDM4E B2RXH2 2/20 0.40
ALDH1A1 P00352 2/20 0.40
GLA P06280 1/20 0.40
MAPT P10636 1/20 0.40
MCL1 Q07820 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14998127 0.93 NFE2L2 (0.47) NFE2L2KMT2ARAB9ASMN1; SMN2NPC1
SCHEMBL8400512 0.87 NFE2L2 (0.49) NFE2L2KMT2ARAB9ASMN1; SMN2NPC1
SCHEMBL10527135 0.85 NFE2L2 (0.48) NFE2L2KMT2ARAB9ASMN1; SMN2NPC1
SCHEMBL1732259 0.83 KMT2A (0.41) NFE2L2KMT2ARAB9ASMN1; SMN2NPC1
SCHEMBL8034595 0.82 HPGD (0.50) KMT2ARAB9ASMN1; SMN2NPC1POLB
SCHEMBL58567 0.81 NFE2L2 (0.44) NFE2L2KMT2ARAB9ASMN1; SMN2NPC1
SCHEMBL14570823 0.81 KMT2A (0.39) NFE2L2KMT2ARAB9ASMN1; SMN2NPC1
SCHEMBL15158 0.79 LMNA (0.40) KMT2ARAB9ASMN1; SMN2NPC1HTT
SCHEMBL14570827 0.79 KMT2A (0.38) NFE2L2KMT2ARAB9ASMN1; SMN2NPC1
SCHEMBL30037473 0.79 CES2 (0.53) KMT2ARAB9ASMN1; SMN2NPC1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113166621-B Multiple composite material based on glass resin composite material 米其林集团总公司 2022-08-16 CN disclosed
CN-113166622-B Multiple composite material based on glass resin composite material 米其林集团总公司 2022-08-02 CN disclosed
CN-113166621-A Multiple composite material based on glass resin composite material 米其林集团总公司 2021-07-23 CN disclosed
CN-113166622-A Multiple composite material based on glass resin composite material 米其林集团总公司 2021-07-23 CN disclosed
EP-1379378-A2 HIGH VOLUME LENS CURING SYSTEM Q2100, INC. (US) 2004-01-14 EP disclosed
WO-2002066237-A2 HIGH VOLUME LENS CURING SYSTEM Q2100, INC. (US) 2002-08-29 WO disclosed