Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 8/20 | 0.35 |
| ▸ | CA1 | P00915 | 8/20 | 0.35 |
| ▸ | CA2 | P00918 | 8/20 | 0.35 |
| ▸ | CA9 | Q16790 | 8/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | FUT8 | Q9BYC5 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17323123 | 0.86 | SIGMAR1 (0.41) | SIGMAR1CA12CA1CA2CA9 | |
| SCHEMBL17323132 | 0.84 | NFKB1 (0.39) | SIGMAR1CA12CA1CA2CA9 | |
| SCHEMBL17323133 | 0.77 | ATIC (0.40) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL15985820 | 0.74 | FUT8 (0.46) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL17327033 | 0.73 | FUT8 (0.44) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL17323129 | 0.71 | ENPP2 (0.39) | CA12CA1CA2CA9FUT8 | |
| SCHEMBL15985954 | 0.71 | FUT8 (0.42) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL14159926 | 0.71 | CA12 (0.46) | SIGMAR1CA12CA1CA2CA9 | |
| SCHEMBL17323122 | 0.70 | NFKB1 (0.39) | SIGMAR1CA12CA1CA2CA9 | |
| SCHEMBL14094980 | 0.70 | CA12 (0.39) | CA12CA1CA2CA9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9540765-B2 | Mixtures of reactive dyes and their use in a method of di- or trichromatic dyeing or printing | HUNTSMAN INTERNATIONAL LLC (US) | 2017-01-10 | — | — | US | disclosed |
| US-20150354134-A1 | Mixtures of Reactive Dyes and Their Use in a Method of Di- or Trichromatic Dyeing or Printing | HUNTSMAN INTERNATIONAL LLC | 2015-12-10 | — | — | US | disclosed |