Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | ESRRB | O95718 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23731932 | 0.82 | POLB (0.46) | POLBTSHRALDH1A1LMNAKDM4E | |
| SCHEMBL759613 | 0.82 | POLB (0.46) | POLBTSHRALDH1A1LMNAKDM4E | |
| Bromide SCHEMBL29024015 | 0.81 | POLB (0.44) | POLBTSHRALDH1A1LMNAKDM4E | |
| SCHEMBL27709660 | 0.76 | ALDH1A1 (0.46) | POLBTSHRALDH1A1LMNAKDM4E | |
| SCHEMBL19120744 | 0.73 | OPRM1 (0.41) | SMN1; SMN2MAPK1CA12CA9KMT2A | |
| SCHEMBL9524467 | 0.72 | ALDH1A1 (0.50) | POLBTSHRALDH1A1LMNAKDM4E | |
| SCHEMBL12231875 | 0.72 | SMN1; SMN2 (0.41) | POLBSMN1; SMN2HSD17B10HPGDMAPK1 | |
| SCHEMBL11095550 | 0.71 | TSHR (0.42) | POLBTSHRALDH1A1LMNAKDM4E | |
| SCHEMBL9329405 | 0.70 | POLB (0.46) | POLBTSHRALDH1A1LMNAKDM4E | |
| SCHEMBL1629392 | 0.69 | ALDH1A1 (0.44) | POLBTSHRALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9315531-B2 | Titanocene-gold derivatives comprising thiolato ligands | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2016-04-19 | — | — | US | disclosed |
| US-20150353591-A1 | TITANOCENE-GOLD DERIVATIVES COMPRISING THIOLATO LIGANDS | UNIVERSITY OF HAWAII | 2015-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353591-A1 | TITANOCENE-GOLD DERIVATIVES COMPRISING THIOLATO LIGANDS | MUC1, TP53, EPCAM | POLB 2962/4885TSHR 102/4885ALDH1A1 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.