Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.37 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.32 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14861216 | 0.76 | GABRR1 (0.48) | TSHRTP53EGLN1EGLN3HCAR2 | |
| SCHEMBL14861215 | 0.76 | GABRR1 (0.48) | TSHRTP53EGLN1EGLN3HCAR2 | |
| SCHEMBL277485 | 0.76 | HCAR2 (0.46) | TSHRTP53EGLN1EGLN3ALDH1A1 | |
| SCHEMBL9700716 | 0.74 | TSHR (0.41) | TSHRTP53EGLN1EGLN3HCAR2 | |
| Maleic Acid SCHEMBL532212 | 0.69 | — | — | |
| Fumaric Acid SCHEMBL532213 | 0.69 | — | — | |
| Fumaric Acid SCHEMBL3739893 | 0.69 | — | — | |
| Glutaconate SCHEMBL8088023 | 0.69 | ALDH1A1 (0.61) | TSHRTP53EGLN1EGLN3ALDH1A1 | |
| SCHEMBL2721423 | 0.69 | TSHR (0.53) | TSHRTP53EGLN1EGLN3ALDH1A1 | |
| SCHEMBL9311666 | 0.69 | TSHR (0.53) | TSHRTP53EGLN1EGLN3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150352519-A1 | METAL ORGANIC FRAMEWORKS FOR ELECTRONIC GAS STORAGE | NUMAT TECHNOLOGIES INC (US) | 2015-12-10 | — | — | US | disclosed |