Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 4/20 | 0.57 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17326282 | 0.90 | HPGD (0.68) | MAPK1HSD17B10HPGDALDH1A1POLB | |
| SCHEMBL17326498 | 0.87 | POLB (0.67) | MAPK1HSD17B10HPGDALDH1A1POLB | |
| SCHEMBL14947001 | 0.84 | MAPK1 (0.81) | MAPK1HSD17B10HPGDALDH1A1POLB | |
| SCHEMBL17326730 | 0.83 | HPGD (0.62) | MAPK1HSD17B10HPGDALDH1A1POLB | |
| SCHEMBL13899508 | 0.82 | MEN1 (0.59) | MAPK1HPGDALDH1A1POLBBRD4 | |
| SCHEMBL17326722 | 0.81 | CYP2C9 (0.60) | MAPK1HSD17B10HPGDALDH1A1POLB | |
| SCHEMBL14384855 | 0.79 | HSD17B10 (0.72) | MAPK1HSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL14010049 | 0.79 | BRD4 (0.56) | MAPK1HSD17B10HPGDALDH1A1POLB | |
| SCHEMBL16917060 | 0.78 | HSD17B10 (0.57) | MAPK1HSD17B10HPGDALDH1A1POLB | |
| SCHEMBL14384846 | 0.78 | MTNR1A (0.64) | MAPK1HSD17B10HPGDALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015185785-A1 | DERIVATIVES OF ISOINDOLIN-1,3-DIONE | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) | 2015-12-10 | — | — | WO | disclosed |