Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17326282 | 0.88 | HPGD (0.68) | HPGDHSD17B10ALDH1A1NPSR1POLB | |
| SCHEMBL17326722 | 0.84 | CYP2C9 (0.60) | HPGDHSD17B10ALDH1A1NPSR1POLB | |
| SCHEMBL17326506 | 0.83 | MAPK1 (0.75) | HPGDHSD17B10ALDH1A1NPSR1POLB | |
| SCHEMBL17326498 | 0.81 | POLB (0.67) | HPGDHSD17B10ALDH1A1POLBBRD4 | |
| SCHEMBL10264545 | 0.76 | SMN1; SMN2 (0.67) | HSD17B10POLBMEN1KMT2ALMNA | |
| SCHEMBL10593088 | 0.74 | HPGD (0.60) | HPGDHSD17B10ALDH1A1NPSR1MAPK1 | |
| SCHEMBL17326261 | 0.73 | LMNA (0.55) | ALDH1A1POLBMAPK1MEN1KMT2A | |
| SCHEMBL17326661 | 0.73 | KMT2A (0.60) | HPGDHSD17B10ALDH1A1NPSR1POLB | |
| SCHEMBL11862277 | 0.72 | KDM4E (0.74) | HPGDHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL14338249 | 0.72 | MTNR1B (0.69) | HPGDHSD17B10ALDH1A1POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015185785-A1 | DERIVATIVES OF ISOINDOLIN-1,3-DIONE | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) | 2015-12-10 | — | — | WO | disclosed |