Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.60 |
| ▸ | MEN1 | O00255 | 6/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17326282 | 0.84 | HPGD (0.68) | KMT2AMEN1HTTALDH1A1MAPT | |
| SCHEMBL17326281 | 0.75 | MEN1 (0.53) | KMT2AMEN1HTTALDH1A1MAPT | |
| SCHEMBL17326498 | 0.75 | POLB (0.67) | KMT2AMEN1ALDH1A1HPGDPOLB | |
| SCHEMBL17326506 | 0.74 | MAPK1 (0.75) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL14384694 | 0.74 | TTR (0.60) | KMT2AMEN1HTTALDH1A1MAPT | |
| SCHEMBL10013240 | 0.74 | ALDH1A1 (0.65) | KMT2AMEN1HTTALDH1A1MAPT | |
| SCHEMBL261725 | 0.74 | BRD4 (0.68) | KMT2AMEN1HTTALDH1A1MAPT | |
| SCHEMBL17326730 | 0.73 | HPGD (0.62) | KMT2AMEN1HTTALDH1A1MAPT | |
| SCHEMBL17326722 | 0.71 | CYP2C9 (0.60) | KMT2AMEN1ALDH1A1HPGDPOLB | |
| SCHEMBL30492996 | 0.71 | SMN1; SMN2 (0.68) | KMT2AMEN1HTTALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015185785-A1 | DERIVATIVES OF ISOINDOLIN-1,3-DIONE | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) | 2015-12-10 | — | — | WO | disclosed |