SCHEMBL17329465

SCHEMBL17329465

CCOC(=O)C(C#N)=Cc1ccc(Oc2ccc(C=C(C#N)C(=O)OCC)cc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.71
MAPT P10636 7/20 0.71
KDM4E B2RXH2 3/20 0.71
PKM P14618 1/20 0.64
HTT P42858 1/20 0.64
KMT2A Q03164 6/20 0.63
MEN1 O00255 5/20 0.63
L3MBTL1 Q9Y468 2/20 0.63
TDP1 Q9NUW8 2/20 0.63
NPC1 O15118 1/20 0.63
MAPK1 P28482 1/20 0.63
CASP3 P42574 1/20 0.63
RAB9A P51151 1/20 0.63
SENP8 Q96LD8 1/20 0.63
SENP7 Q9BQF6 1/20 0.63
SENP6 Q9GZR1 1/20 0.63
PDCD1 Q15116 1/20 0.60
CD274 Q9NZQ7 1/20 0.60
CRHBP P24387 1/20 0.60
CRHR2 Q13324 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15371840 1.00 ALDH1A1 (0.71) ALDH1A1MAPTKDM4EPKMHTT
SCHEMBL16131599 0.95 ALDH1A1 (0.64) ALDH1A1MAPTKDM4EPKMHTT
SCHEMBL4317761 0.92 ALDH1A1 (0.81) ALDH1A1MAPTKDM4EPKMHTT
SCHEMBL2139676 0.92 ALDH1A1 (0.81) ALDH1A1MAPTKDM4EPKMHTT
SCHEMBL2139678 0.92 ALDH1A1 (0.81) ALDH1A1MAPTKDM4EPKMHTT
SCHEMBL3602307 0.90 ALDH1A1 (0.70) ALDH1A1MAPTKDM4EPKMHTT
SCHEMBL21457762 0.90 ALDH1A1 (0.69) ALDH1A1MAPTKDM4EPKMHTT
SCHEMBL21457759 0.90 ALDH1A1 (0.69) ALDH1A1MAPTKDM4EPKMHTT
SCHEMBL19988422 0.90 ALDH1A1 (0.70) ALDH1A1MAPTKDM4EPKMHTT
SCHEMBL3602305 0.90 ALDH1A1 (0.70) ALDH1A1MAPTKDM4EPKMHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10090163-B2 Inorganic film-forming composition for multilayer resist processes, and pattern-forming method JSR CORPORATION (JP) 2018-10-02 US disclosed
US-20150364332-A1 INORGANIC FILM-FORMING COMPOSITION FOR MULTILAYER RESIST PROCESSES, AND PATTERN-FORMING METHOD JSR CORPORATION (JP) 2015-12-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10090163-B2 Inorganic film-forming composition for multilayer resist processes, and pattern-forming method HCAR1, HSD17B7, BMPR1A ALDH1A1 749/4885MAPT 3163/4885KDM4E 1112/4885
US-20150364332-A1 INORGANIC FILM-FORMING COMPOSITION FOR MULTILAYER RESIST PROCESSES, AND PATTERN-FORMING METHOD HCAR1, HSD17B7, BMPR1A ALDH1A1 749/4885MAPT 3163/4885KDM4E 1112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.