SCHEMBL17336285

SCHEMBL17336285

CCCCNCC(N)CCCC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
ANPEP P15144 2/20 0.43
ERAP2 Q6P179 1/20 0.43
ALDH1A1 P00352 2/20 0.41
CYP3A4 P08684 1/20 0.41
DPP7 Q9UHL4 1/20 0.37
SLC15A1 P46059 1/20 0.37
PLA2G1B P04054 1/20 0.36
PLA2G2A P14555 1/20 0.36
OPRM1 P35372 1/20 0.36
ADH1B P00325 1/20 0.34
ADH1C P00326 1/20 0.34
ADH1A P07327 1/20 0.34
ADH7 P40394 1/20 0.34
MEN1 O00255 1/20 0.34
NOS3 P29474 1/20 0.34
NOS1 P29475 1/20 0.34
KMT2A Q03164 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
S1PR2 O95136 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5085745 0.90 CASP2 (0.41) TSHRANPEPERAP2ALDH1A1CYP3A4
SCHEMBL8435126 0.89 TDP1 (0.43) TSHRANPEPERAP2ALDH1A1CYP3A4
SCHEMBL11410868 0.88 ANPEP (0.39) TSHRANPEPERAP2ALDH1A1CYP3A4
SCHEMBL12952257 0.88 GNAI3 (0.42) TSHRANPEPERAP2ALDH1A1MEN1
SCHEMBL30512648 0.87 TSHR (0.41) TSHRANPEPERAP2ALDH1A1CYP3A4
SCHEMBL11791450 0.87 ANPEP (0.53) TSHRANPEPERAP2ALDH1A1PLA2G1B
SCHEMBL11801411 0.87 ANPEP (0.53) TSHRANPEPERAP2ALDH1A1PLA2G1B
SCHEMBL27440938 0.85 ALDH1A1 (0.38) TSHRANPEPERAP2ALDH1A1CYP3A4
SCHEMBL28134166 0.84 TSHR (0.43) TSHRALDH1A1CYP3A4DPP7SLC15A1
SCHEMBL23154833 0.84 TSHR (0.46) TSHRANPEPERAP2ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3154937-B1 CHLORINE-RESISTANT POLYETHYLENE COMPOUND AND ARTICLES MADE THEREFROM FINA TECHNOLOGY (US) 2024-05-22 EP claimed
US-10584823-B2 Chlorine-resistant polyethylene compound and articles made therefrom FINA TECHNOLOGY, INC. (US) 2020-03-10 US claimed
EP-3154937-A1 CHLORINE-RESISTANT POLYETHYLENE COMPOUND AND ARTICLES MADE THEREFROM Fina Technology, Inc. (US) 2017-04-19 EP claimed
US-20170089503-A1 Chlorine-resistant Polyethylene Compound and Articles Made Therefrom TOTAL AMERICAN SERVICES, INC. 2017-03-30 US claimed
WO-2015191721-A1 CHLORINE-RESISTANT POLYETHYLENE COMPOUND AND ARTICLES MADE THEREFROM FINA TECHNOLOGY, INC. (US) 2015-12-17 WO claimed
EP-3154937-B1 CHLORINE-RESISTANT POLYETHYLENE COMPOUND AND ARTICLES MADE THEREFROM FINA TECHNOLOGY (US) 2024-05-22 EP disclosed
US-10584823-B2 Chlorine-resistant polyethylene compound and articles made therefrom FINA TECHNOLOGY, INC. (US) 2020-03-10 US disclosed
EP-3154937-A1 CHLORINE-RESISTANT POLYETHYLENE COMPOUND AND ARTICLES MADE THEREFROM Fina Technology, Inc. (US) 2017-04-19 EP disclosed
US-20170089503-A1 Chlorine-resistant Polyethylene Compound and Articles Made Therefrom TOTAL AMERICAN SERVICES, INC. 2017-03-30 US disclosed
WO-2015191721-A1 CHLORINE-RESISTANT POLYETHYLENE COMPOUND AND ARTICLES MADE THEREFROM FINA TECHNOLOGY, INC. (US) 2015-12-17 WO disclosed