Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19300979 | 0.84 | MEN1 (0.34) | TDP1DPP7 | |
| SCHEMBL17336285 | 0.84 | TSHR (0.44) | TSHRALDH1A1CYP3A4SLC15A1PLA2G1B | |
| SCHEMBL17336278 | 0.82 | ALDH1A1 (0.45) | TSHRALDH1A1CYP3A4SLC15A1PLA2G1B | |
| SCHEMBL13973040 | 0.82 | GNAI3 (0.35) | TSHRALDH1A1TDP1DPP7DNM1 | |
| SCHEMBL8435126 | 0.82 | TDP1 (0.43) | TSHRALDH1A1CYP3A4SLC15A1PLA2G1B | |
| SCHEMBL30420362 | 0.79 | TSHR (0.50) | TSHRALDH1A1CYP3A4SLC15A1PLA2G1B | |
| SCHEMBL27440938 | 0.79 | ALDH1A1 (0.38) | TSHRALDH1A1CYP3A4SLC15A1PLA2G1B | |
| SCHEMBL5085745 | 0.79 | CASP2 (0.41) | TSHRALDH1A1CYP3A4TDP1SMN1; SMN2 | |
| SCHEMBL14528628 | 0.78 | — | — | |
| SCHEMBL15623972 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106458883-A | Chlorine resistant polyethylene compounds and articles made therefrom | 弗纳技术股份有限公司 | 2017-02-22 | — | — | CN | claimed |