Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21337184 | 0.82 | DNM1 (0.35) | OPRM1DNM1ALDH1A1MEN1KMT2A | |
| SCHEMBL7149510 | 0.82 | OPRM1 (0.30) | OPRM1 | |
| SCHEMBL20357565 | 0.80 | — | — | |
| SCHEMBL23027392 | 0.80 | DNM1 (0.33) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL19926761 | 0.79 | ALDH1A1 (0.33) | OPRM1SPHK1TRPV1TRPA1ALDH1A1 | |
| SCHEMBL21111477 | 0.79 | ALDH1A1 (0.33) | OPRM1SPHK1TRPV1TRPA1ALDH1A1 | |
| SCHEMBL2066948 | 0.79 | ALDH1A1 (0.35) | OPRM1ALDH1A1TSHR | |
| SCHEMBL13128007 | 0.78 | DNM1 (0.32) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL9187102 | 0.78 | OPRM1 (0.33) | OPRM1SPHK1TRPV1TRPA1DNM1 | |
| SCHEMBL21118226 | 0.77 | METAP1 (0.43) | OPRM1SPHK1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9211250-B2 | Heterogeneous polymeric micelles for intracellular delivery | UNIVERSITY OF WASHINGTON (US) | 2015-12-15 | — | — | US | disclosed |