Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.42 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15418891 | 0.83 | NR4A2 (0.50) | NR4A2CYP2C9MCHR1ALDH1A1 | |
| SCHEMBL1733130 | 0.80 | NR4A2 (0.73) | NR4A2CYP2C9MCHR1EGLN1 | |
| SCHEMBL1733303 | 0.78 | ALDH1A1 (0.38) | NR4A2CYP2C9ALDH1A1ALDH1A3ALDH1A2 | |
| SCHEMBL1728471 | 0.78 | NR4A2 (0.70) | NR4A2CYP2C9MCHR1EGLN1 | |
| SCHEMBL1733053 | 0.78 | ENPP2 (0.39) | NR4A2CYP2C9ALDH1A1ALDH1A3ALDH1A2 | |
| Hydrochloric Acid SCHEMBL3777031 | 0.77 | NR4A2 (0.69) | NR4A2CYP2C9MCHR1EGLN1 | |
| SCHEMBL15418882 | 0.77 | ALDH1A1 (0.37) | NR4A2CYP2C9ALDH1A1ALDH1A3ALDH1A2 | |
| Hydrochloric Acid SCHEMBL3766428 | 0.77 | NR4A2 (0.69) | NR4A2CYP2C9MCHR1EGLN1 | |
| SCHEMBL1733988 | 0.75 | MAP3K5 (0.51) | ALDH1A1ALDH1A3ALDH1A2EGLN1 | |
| SCHEMBL1735826 | 0.74 | ADORA2A (0.59) | NR4A2ALDH1A1ALDH1A3ALDH1A2EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2225240-B1 | Derivatives of 6-heterocyclic-imidazo[1,2-a]pyridine-2-carboxamides, preparation thereof and therapeutic application thereof | SANOFI SA (FR) | 2014-01-22 | — | — | EP | claimed |
| EP-2225243-B1 | Derivatives of N-heterocyclic-6-heterocyclic-imidazo[1,2-a]pyridine-2-carboxamides, preparation thereof and therapeutic application thereof | SANOFI SA (FR) | 2011-11-16 | — | — | EP | claimed |