Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.48 |
| ▸ | PRTN3 | P24158 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | KLK1 | P06870 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12621327 | 1.00 | ELANE (0.48) | ELANEPRTN3TP53KLK1ALDH1A1 | |
| SCHEMBL12621337 | 0.93 | TP53 (0.49) | ELANEPRTN3TP53ALDH1A1PTPN1 | |
| SCHEMBL12621338 | 0.90 | PTPN1 (0.47) | ELANEPTPN1PLAUPTPRC | |
| SCHEMBL12621330 | 0.88 | RAB9A (0.46) | ALDH1A1 | |
| SCHEMBL12621326 | 0.86 | LMNA (0.45) | ALDH1A1 | |
| SCHEMBL441596 | 0.83 | KCNN4 (0.42) | ELANEALDH1A1 | |
| SCHEMBL17902756 | 0.80 | SRC (0.44) | ALDH1A1 | |
| SCHEMBL21024257 | 0.79 | TP53 (0.48) | ELANEPRTN3TP53KLK1ALDH1A1 | |
| SCHEMBL21024244 | 0.78 | FKBP1A (0.35) | ELANEALDH1A1PTPN1PTPRCSMN1; SMN2 | |
| SCHEMBL12654689 | 0.77 | ALDH1A1 (0.53) | ALDH1A1PTPN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2955190-A2 | Chemical compounds | NuCana BioMed Limited (GB) | 2015-12-16 | — | — | EP | disclosed |