Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17951489 | 0.70 | PTPRC (0.35) | — | |
| SCHEMBL23170937 | 0.70 | PTPRC (0.33) | — | |
| SCHEMBL17340929 | 0.67 | KDM4E (0.32) | KDM4ESMN1; SMN2 | |
| SCHEMBL17951779 | 0.66 | PTPRC (0.40) | — | |
| SCHEMBL17340907 | 0.66 | KDM4E (0.32) | KDM4ESMN1; SMN2 | |
| SCHEMBL19135367 | 0.65 | — | — | |
| SCHEMBL891151 | 0.65 | HPGD (0.44) | KDM4ESMN1; SMN2 | |
| SCHEMBL17340914 | 0.64 | KDM4E (0.31) | KDM4ESMN1; SMN2 | |
| SCHEMBL17341312 | 0.64 | KDM4E (0.31) | KDM4ESMN1; SMN2 | |
| SCHEMBL17340897 | 0.62 | ALDH1A1 (0.41) | KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9708528-B2 | Robust photochromic compounds with silicon- or phosphorus-containing heterocyclic ring and the production thereof | THE UNIVERSITY OF HONG KONG (HK) | 2017-07-18 | — | — | US | disclosed |
| US-20150361332-A1 | ROBUST PHOTOCHROMIC COMPOUNDS WITH SILICON- OR PHOSPHORUS-CONTAINING HETEROCYCLIC RING AND THE PRODUCTION THEREOF | THE UNIVERSITY OF HONG KONG (HK) | 2015-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150361332-A1 | ROBUST PHOTOCHROMIC COMPOUNDS WITH SILICON- OR PHOSPHORUS-CONTAINING HETEROCYCLIC RING AND THE PRODUCTION THEREOF | CRY1, CRY2, P2RY10 | KDM4E 641/4885SMN1; SMN2 1647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.