Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3423443 | 0.73 | ALDH1A1 (0.44) | KDM4ESMN1; SMN2ALDH1A1HTTNPSR1 | |
| SCHEMBL891066 | 0.71 | HPGD (0.41) | HPGDKDM4EALDH1A1MAPTTSHR | |
| SCHEMBL11367086 | 0.70 | HPGD (0.59) | HPGDSMN1; SMN2MAPTTSHRLMNA | |
| SCHEMBL12091657 | 0.65 | ALDH1A1 (0.40) | HPGDKDM4ESMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL7194664 | 0.65 | ALDH1A1 (0.50) | HPGDKDM4ESMN1; SMN2ALDH1A1HTT | |
| SCHEMBL17340922 | 0.65 | KDM4E (0.32) | KDM4ESMN1; SMN2 | |
| SCHEMBL17340929 | 0.62 | KDM4E (0.32) | KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL13382629 | 0.61 | ALDH1A1 (0.44) | KDM4ESMN1; SMN2ALDH1A1MAPTPLA2G10 | |
| SCHEMBL19135544 | 0.61 | ALDH1A1 (0.40) | HPGDKDM4ESMN1; SMN2ALDH1A1HTT | |
| SCHEMBL439365 | 0.61 | HPGD (1.00) | HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722076-B2 | Photochrome- or near IR dye-coupled polymeric matrices for medical articles | SURMODICS, INC. (US) | 2014-05-13 | — | — | US | disclosed |
| US-20120082713-A1 | PHOTOCHROME- OR NEAR IR DYE-COUPLED POLYMERIC MATRICES FOR MEDICAL ARTICLES | BANK OF MONTREAL, AS COLLATERAL AGENT | 2012-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120082713-A1 | PHOTOCHROME- OR NEAR IR DYE-COUPLED POLYMERIC MATRICES FOR MEDICAL ARTICLES | IK, PIR, PLOD1 | HPGD 1754/4885KDM4E 2503/4885SMN1; SMN2 2269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.