SCHEMBL173455

SCHEMBL173455

N=C(Nc1ccccc1F)Nc1ccccc1F

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 10/20 0.61
NPC1 O15118 8/20 0.61
SMN1; SMN2 Q16637 5/20 0.61
MEN1 O00255 4/20 0.52
KMT2A Q03164 4/20 0.52
HTT P42858 3/20 0.50
ALDH1A1 P00352 4/20 0.48
POLB P06746 1/20 0.48
MAPT P10636 3/20 0.47
GAA P10253 1/20 0.47
NPSR1 Q6W5P4 1/20 0.46
LMNA P02545 1/20 0.46
PDK1 Q15118 1/20 0.46
PDK2 Q15119 1/20 0.46
PDK3 Q15120 1/20 0.46
PDK4 Q16654 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30050422 1.00 RAB9A (0.61) RAB9ANPC1SMN1; SMN2MEN1KMT2A
SCHEMBL29278834 0.90 NPC1 (0.57) RAB9ANPC1SMN1; SMN2MEN1KMT2A
SCHEMBL4100748 0.84 RAB9A (0.50) RAB9ANPC1SMN1; SMN2MEN1KMT2A
Hydrochloric Acid SCHEMBL16701880 0.82 RAB9A (0.48) RAB9ANPC1SMN1; SMN2MEN1KMT2A
SCHEMBL4682179 0.82 RAB9A (0.48) RAB9ANPC1SMN1; SMN2MEN1KMT2A
SCHEMBL29430234 0.82 RAB9A (0.48) RAB9ANPC1SMN1; SMN2MEN1KMT2A
SCHEMBL11879308 0.82 RAB9A (0.57) RAB9ANPC1SMN1; SMN2MEN1KMT2A
SCHEMBL31607070 0.82 RAB9A (0.57) RAB9ANPC1SMN1; SMN2MEN1KMT2A
SCHEMBL4100747 0.81 RAB9A (0.56) RAB9ANPC1SMN1; SMN2MEN1KMT2A
SCHEMBL28014771 0.80 RAB9A (0.55) RAB9ANPC1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11559763-B2 Regenerable solvent mixtures for acid-gas separation RESEARCH TRIANGLE INSTITUTE (US) 2023-01-24 US claimed
US-20260007998-A1 REGENERABLE SOLVENT MIXTURES FOR ACID-GAS SEPARATION RES TRIANGLE INST (US) 2026-01-08 US disclosed
US-12427471-B2 Regenerable solvent mixtures for acid-gas separation RESEARCH TRIANGLE INSTITUTE (NC) 2025-09-30 US disclosed
EP-4359111-A1 MBZA/PEG ETHYL ETHER BASED LIQUID SOLVENT CO2 CAPTURE IN ROTATING PACKED BED Research Triangle Institute (US) 2024-05-01 EP disclosed
US-20230241547-A1 REGENERABLE SOLVENT MIXTURES FOR ACID-GAS SEPARATION RES TRIANGLE INST (US) 2023-08-03 US disclosed
US-11612854-B2 Non-aqueous solvent CO2 capture in rotating packed bed RESEARCH TRIANGLE INSTITUTE (US) 2023-03-28 US disclosed
US-11559763-B2 Regenerable solvent mixtures for acid-gas separation RESEARCH TRIANGLE INSTITUTE (US) 2023-01-24 US disclosed
WO-2022269546-A1 MBZA/PEG ETHYL ETHER BASED LIQUID SOLVENT CO2 CAPTURE IN ROTATING PACKED BED RESEARCH TRIANGLE INSTITUTE (US) 2022-12-29 WO disclosed
US-20220410063-A1 NON-AQUEOUS SOLVENT CO2 CAPTURE IN ROTATING PACKED BED RESEARCH TRIANGLE INSTITUTE 2022-12-29 US disclosed
US-20210178316-A1 REGENERABLE SOLVENT MIXTURES FOR ACID-GAS SEPARATION RES TRIANGLE INST (US) 2021-06-17 US disclosed
US-10960345-B2 Regenerable solvent mixtures for acid-gas separation RESEARCH TRIANGLE INSTITUTE (NC) 2021-03-30 US disclosed
EP-2819767-B1 REGENERABLE SOLVENT MIXTURES FOR ACID-GAS SEPARATION RES TRIANGLE INST (US) 2019-09-11 EP disclosed
US-20180345206-A1 REGENERABLE SOLVENT MIXTURES FOR ACID-GAS SEPARATION RES TRIANGLE INST (US) 2018-12-06 US disclosed
US-10065148-B2 Regenerable solvent mixtures for acid-gas separation RESEARCH TRIANGLE INSTITUTE (US) 2018-09-04 US disclosed
US-9839875-B2 Regenerable solvent mixtures for acid-gas separation RESEARCH TRIANGLE INSTITUTE (US) 2017-12-12 US disclosed
EP-2611518-B1 REGENERABLE IONIC LIQUID SOLVENTS FOR ACID-GAS SEPARATION RES TRIANGLE INST (US) 2016-08-24 EP disclosed
US-20150328581-A1 REGENERABLE SOLVENT MIXTURES FOR ACID-GAS SEPARATION RES TRIANGLE INST (US) 2015-11-19 US disclosed
EP-2611518-A1 REGENERABLE IONIC LIQUID SOLVENTS FOR ACID -GAS SEPARATION Research Triangle Institute (US) 2013-07-10 EP disclosed
US-20130164199-A1 REGENERABLE SOLVENT MIXTURES FOR ACID-GAS SEPARATION RESEARCH TRIANGLE INSTITUTE 2013-06-27 US disclosed
WO-2012031274-A1 REGENERABLE IONIC LIQUID SOLVENTS FOR ACID -GAS SEPARATION RESEARCH TRIANGLE INSTITUTE (US) 2012-03-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260007998-A1 REGENERABLE SOLVENT MIXTURES FOR ACID-GAS SEPARATION NOS2, DUOX2, SMOX RAB9A 2784/4885NPC1 4415/4885SMN1; SMN2 1262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.