SCHEMBL17346399

SCHEMBL17346399

CCN(C)CCCN(CCSc1ccccc1)Cc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACKR3 P25106 1/20 0.44
BCHE P06276 6/20 0.41
ACHE P22303 6/20 0.41
SLC2A1 P11166 1/20 0.41
SIGMAR1 Q99720 1/20 0.41
CHRM2 P08172 1/20 0.41
HTR1A P08908 1/20 0.41
ADRA2A P08913 1/20 0.41
CHRM1 P11229 1/20 0.41
DRD1 P21728 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
ADRA1A P35348 1/20 0.41
OPRM1 P35372 1/20 0.41
DRD3 P35462 1/20 0.41
SLC6A3 Q01959 1/20 0.41
KCNH2 Q12809 1/20 0.41
FDPS P14324 2/20 0.40
MAOB P27338 2/20 0.39
CNR2 P34972 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17346020 0.89 SLC2A1 (0.48) ACKR3BCHEACHESLC2A1SIGMAR1
SCHEMBL17346327 0.87 HTT (0.47) ACKR3SIGMAR1HTR1ASLC6A4ALDH1A1
SCHEMBL18677932 0.86 HTR7 (0.49) ACKR3BCHEACHESLC2A1MAOB
SCHEMBL17346349 0.84 FDPS (0.51) ACKR3SLC2A1SIGMAR1CHRM2HTR1A
SCHEMBL17346348 0.83 BCHE (0.41) BCHEACHESIGMAR1CHRM2HTR1A
SCHEMBL17345931 0.81 HTT (0.47) ACKR3SLC2A1SIGMAR1FDPSALDH1A1
SCHEMBL17345995 0.81 SLC2A1 (0.59) BCHEACHESLC2A1SIGMAR1CHRM2
SCHEMBL17346044 0.80 ACKR3 (0.49) ACKR3SLC2A1SIGMAR1FDPSMAOB
SCHEMBL26618228 0.80 ALDH1A1 (0.54) SLC2A1HTR1ASLC6A4FDPSMAOB
SCHEMBL10560546 0.80 ALDH1A1 (0.42) ACKR3BCHESLC2A1OPRM1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170088571-A1 POLYDENTATE LIGANDS AND THEIR COMPLEXES FOR MOLECULAR CATALYSIS TRIAD NATIONAL SECURITY, LLC 2017-03-30 US disclosed
US-20170088571-A1 POLYDENTATE LIGANDS AND THEIR COMPLEXES FOR MOLECULAR CATALYSIS TRIAD NATIONAL SECURITY, LLC 2017-03-30 US disclosed
WO-2015191505-A1 POLYDENTATE LIGANDS AND THEIR COMPLEXES FOR MOLECULAR CATALYSIS LOS ALAMOS NATIONAL SECURITY, LLC (US) 2015-12-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170088571-A1 POLYDENTATE LIGANDS AND THEIR COMPLEXES FOR MOLECULAR CATALYSIS NANS, NCL, NCLN ACKR3 1678/4885BCHE 1165/4885ACHE 1215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.