Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1108695 | 0.89 | ALDH1A1 (0.38) | MAPTKDM4ENPC1ALDH1A1GFER | |
| SCHEMBL12587556 | 0.87 | ESR2 (0.38) | MAPTKDM4ENPC1ALDH1A1GFER | |
| SCHEMBL16449477 | 0.87 | ALDH1A1 (0.37) | MAPTKDM4ENPC1ALDH1A1GFER | |
| SCHEMBL12708060 | 0.86 | MAPT (0.34) | MAPTKDM4ENPC1ALDH1A1GFER | |
| SCHEMBL17849097 | 0.85 | ESR2 (0.37) | MAPTKDM4ENPC1ALDH1A1GFER | |
| SCHEMBL12545055 | 0.85 | ESR2 (0.37) | MAPTKDM4ENPC1ALDH1A1GFER | |
| SCHEMBL4419377 | 0.84 | MAPT (0.35) | MAPTKDM4EMAPK1NPC1ALDH1A1 | |
| SCHEMBL1396169 | 0.84 | MAPT (0.35) | MAPTKDM4EMAPK1NPC1ALDH1A1 | |
| SCHEMBL4407792 | 0.82 | MAPT (0.38) | MAPTKDM4EMAPK1NPC1ALDH1A1 | |
| SCHEMBL19413012 | 0.80 | NPC1 (0.31) | MAPTNPC1ALDH1A1GFERHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154988-B1 | BORYLATED COMPOUNDS | UNIV MANCHESTER (GB) | 2019-01-09 | — | — | EP | disclosed |
| US-10038148-B2 | Borylated compounds | THE UNIVERSITY OF MANCHESTER (GB) | 2018-07-31 | — | — | US | disclosed |
| US-10038148-B2 | Borylated compounds | THE UNIVERSITY OF MANCHESTER (GB) | 2018-07-31 | — | — | US | disclosed |
| US-20170110660-A1 | BORYLATED COMPOUNDS | THE UNIVERSITY OF MANCHESTER (GB) | 2017-04-20 | — | — | US | disclosed |
| US-20170110660-A1 | BORYLATED COMPOUNDS | THE UNIVERSITY OF MANCHESTER (GB) | 2017-04-20 | — | — | US | disclosed |
| WO-2015189627-A1 | BORYLATED COMPOUNDS | THE UNIVERSITY OF MANCHESTER (GB) | 2015-12-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10038148-B2 | Borylated compounds | EYA3, EYA2, BLM | MAPT 3144/4885KDM4E 3553/4885MAPK1 3934/4885 |
| US-20170110660-A1 | BORYLATED COMPOUNDS | EYA3, EYA2, BLM | MAPT 3144/4885KDM4E 3553/4885MAPK1 3934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.