Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31069613 | 0.75 | AURKA (0.47) | CYP2A6TSHRALDH1A1HSD17B10TDP1 | |
| SCHEMBL4298702 | 0.74 | HSD17B10 (0.46) | MAPTNISCHCYP2A6TSHRCYP1A2 | |
| SCHEMBL28089496 | 0.72 | DNMT1 (0.40) | MAPTNISCHCYP2A6TSHRALDH1A1 | |
| SCHEMBL17344803 | 0.71 | MAPT (0.34) | MAPTNISCHCYP2A6TSHRCYP1A2 | |
| SCHEMBL25286955 | 0.70 | MAPT (0.39) | MAPTCYP2A6TSHRCYP1A2ALDH1A1 | |
| SCHEMBL4421747 | 0.70 | ALDH1A1 (0.46) | NISCHCYP2A6TSHRCYP1A2ALDH1A1 | |
| SCHEMBL14982011 | 0.67 | ALDH1A1 (0.38) | MAPTNISCHCYP2A6TSHRCYP1A2 | |
| SCHEMBL868639 | 0.66 | TSHR (0.52) | MAPTCYP2A6TSHRCYP1A2ALDH1A1 | |
| SCHEMBL29716676 | 0.66 | TSHR (0.52) | MAPTCYP2A6TSHRCYP1A2ALDH1A1 | |
| SCHEMBL21508269 | 0.66 | CA12 (0.52) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2952503-B1 | CARBOXYLIC ACID DERIVATIVES AS HIV REPLICATION INHIBITOR | SHIONOGI & CO (JP) | 2019-10-23 | — | — | EP | disclosed |
| US-20150361093-A1 | HIV REPLICATION INHIBITOR | SHIONOGI & CO., LTD. (JP) | 2015-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150361093-A1 | HIV REPLICATION INHIBITOR | RTF2, REV1, PCNA | MAPT 3234/4885NISCH 3284/4885CYP2A6 2412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.