Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4298702 | 0.82 | HSD17B10 (0.46) | ALDH1A1CYP1A2HSD17B10CYP2A6TSHR | |
| SCHEMBL2614669 | 0.77 | ALDH1A1 (0.38) | ALDH1A1CYP1A2HSD17B10HPGDCYP2A6 | |
| SCHEMBL1938502 | 0.73 | LMNA (0.46) | ALDH1A1HSD17B10CYP2A6TSHRHIF1A | |
| SCHEMBL14847735 | 0.72 | CA2 (0.36) | HSP90AA1 | |
| SCHEMBL11337767 | 0.71 | CYP1A2 (0.38) | ALDH1A1CYP1A2HSD17B10HPGDCYP2A6 | |
| SCHEMBL18019601 | 0.70 | CES1 (0.34) | LMNA | |
| SCHEMBL14498201 | 0.68 | CYP1A2 (0.41) | ALDH1A1CYP1A2HSD17B10HPGDCYP2A6 | |
| SCHEMBL19033400 | 0.68 | ALDH1A1 (0.31) | ALDH1A1HSD17B10CYP2A6TSHRMAPT | |
| SCHEMBL17348455 | 0.67 | MAPT (0.42) | ALDH1A1CYP1A2HSD17B10HPGDCYP2A6 | |
| SCHEMBL23074338 | 0.67 | CYP1A2 (0.37) | ALDH1A1CYP1A2HSD17B10HPGDCYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8729294-B2 | Process for producing optically active 3-substituted-3-formyl-2-hydroxypropanoic acid compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-05-20 | — | — | US | disclosed |
| US-20130137880-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-SUBSTITUTED-3-FORMYL-2-HYDROXYPROPANOIC ACID COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137880-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-SUBSTITUTED-3-FORMYL-2-HYDROXYPROPANOIC ACID COMPOUND | HPD, GRHPR, HAAO | ALDH1A1 18/4885CYP1A2 225/4885HSD17B10 164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.