Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTR5A | P47898 | 2/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 4/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | ROS1 | P08922 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.31 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14491948 | 0.75 | NOX1 (0.42) | MEN1KMT2AALOX15HSD17B10BRPF1 | |
| SCHEMBL18944544 | 0.74 | MEN1 (0.36) | MEN1KMT2AALOX15HSD17B10HTR5A | |
| SCHEMBL22292641 | 0.70 | NPC1 (0.52) | MEN1KMT2AALOX15HSD17B10HTR5A | |
| SCHEMBL310398 | 0.68 | HTR5A (0.57) | MEN1KMT2AALOX15HSD17B10HTR5A | |
| SCHEMBL4294892 | 0.68 | MEN1 (0.50) | MEN1KMT2AALOX15HSD17B10HTR5A | |
| SCHEMBL37900 | 0.68 | AHR (0.50) | MEN1KMT2AALOX15HSD17B10BRPF1 | |
| SCHEMBL29483964 | 0.68 | AHR (0.50) | MEN1KMT2AALOX15HSD17B10BRPF1 | |
| SCHEMBL21229055 | 0.67 | MEN1 (0.42) | MEN1KMT2AALOX15HSD17B10HTR5A | |
| SCHEMBL8805855 | 0.64 | BRPF1 (0.47) | MEN1KMT2AALOX15HSD17B10BRPF1 | |
| SCHEMBL8800787 | 0.64 | HSD17B10 (0.44) | MEN1KMT2AALOX15HSD17B10HTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150361093-A1 | HIV REPLICATION INHIBITOR | SHIONOGI & CO., LTD. (JP) | 2015-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150361093-A1 | HIV REPLICATION INHIBITOR | RTF2, REV1, PCNA | MEN1 4391/4885KMT2A 1031/4885ALOX15 3858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.