Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | HK1 | P19367 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GALK1 | P51570 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL315218 | 0.77 | MEN1 (0.47) | MEN1KMT2AKDM4EMAPK1MAPT | |
| SCHEMBL8800787 | 0.77 | HSD17B10 (0.44) | MEN1KMT2AKDM4EMAPK1MAPT | |
| SCHEMBL7404124 | 0.76 | CA12 (0.55) | MEN1KMT2AKDM4EMAPK1MAPT | |
| SCHEMBL5740686 | 0.73 | ALOX15 (0.57) | MEN1KMT2AKDM4EMAPK1MAPT | |
| SCHEMBL37900 | 0.71 | AHR (0.50) | MEN1KMT2AMAPTNPC1ALDH1A1 | |
| SCHEMBL29483964 | 0.71 | AHR (0.50) | MEN1KMT2AMAPTNPC1ALDH1A1 | |
| SCHEMBL310398 | 0.71 | HTR5A (0.57) | MEN1KMT2AKDM4EMAPK1MAPT | |
| SCHEMBL13775958 | 0.70 | ALOX15 (0.39) | MEN1KMT2AKDM4EMAPK1MAPT | |
| SCHEMBL17349232 | 0.68 | MEN1 (0.41) | MEN1KMT2AALDH1A1ALOX15HSD17B10 | |
| SCHEMBL8805855 | 0.67 | BRPF1 (0.47) | MEN1KMT2AMAPTNPC1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020216378-A1 | HETEROCYCLIC COMPOUND, APPLICATION THEREOF, AND COMPOSITION CONTAINING SAME | 健艾仕生物医药有限公司 | 2020-10-29 | — | — | WO | disclosed |
| US-9474793-B2 | Vaccines and methods for prevention and treatment of drug-resistant HIV-1 and hepatitis B virus | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2016-10-25 | — | — | US | disclosed |
| US-20090317418-A1 | VACCINES AND METHODS FOR PREVENTION AND TREATMENT OF DRUG-RESISTANT HIV-1 AND HEPATITIS B VIRUS | THE GOV'T OF USOA as represented by the SECRETARY OF THE DEPT OF HHS (US) | 2009-12-24 | — | — | US | disclosed |
| EP-1866319-A1 | PHOSPHONO-PENT-2-EN-1-YL NUCLEOSIDES AND ANALOGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-12-19 | — | — | EP | disclosed |
| WO-2006137953-A1 | PHOSPHONO-PENT-2-EN-1-YL NUCLEOSIDES AND ANALOGS | THE REGENTS OF THE UNIVERISITY OF CALIFORNIA (US) | 2006-12-28 | — | — | WO | disclosed |
| EP-0536419-B1 | TRICYCLIC TRIAZOLE DERIVATIVES, PRODUCTION AND USE THEREOF | TORAY INDUSTRIES (JP) | 1999-10-13 | — | — | EP | disclosed |
| US-5683998-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTIPAF AGENTS | TORAY INDUSTRIES, INC. (JP) | 1997-11-04 | — | — | US | disclosed |
| US-5478823-A | Antiinflammatory agents, antiallergens; tricyclic triazolo derivative | TORAY INDUSTRIES, INC. (JP) | 1995-12-26 | — | — | US | disclosed |
| EP-0617961-A1 | EOSINOPHIL INFILTRATION INHIBITOR | TORAY INDUSTRIES, INC. (JP) | 1994-10-05 | — | — | EP | disclosed |
| EP-0536419-A1 | TRICYCLIC TRIAZOLE DERIVATIVE, PRODUCTION THEREOF, AND USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1993-04-14 | — | — | EP | disclosed |