SCHEMBL17351685

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17523406	1.00	PTGS2 (0.42)	PTGS2GSTP1ESR1ESR2RAB9A
	SCHEMBL23957896	0.79	CYP2A6 (0.42)	ALDH1A1KDM4EHSD17B10GLAGAA
	SCHEMBL18594367	0.75	ALDH1A1 (0.43)	RAB9ANPC1KMT2AMEN1ALDH1A1
	SCHEMBL30849651	0.75	LMNA (0.42)	ESR2RAB9ANPC1KMT2AMEN1
	SCHEMBL1955363	0.75	ALDH1A1 (0.42)	ALDH1A1KDM4EHSD17B10GLAGAA
	SCHEMBL26021644	0.75	PLA2G7 (0.43)	RAB9ANPC1KMT2AMEN1ALDH1A1
	SCHEMBL25548017	0.75	MAPK14 (0.40)	RAB9ANPC1ARADORA2AADORA1
	SCHEMBL19544356	0.74	SLC22A12 (0.36)	ALDH1A1KDM4EHSD17B10GLAGAA
	SCHEMBL28654496	0.72	GSTP1 (0.52)	GSTP1ESR1ESR2RAB9ANPC1
	SCHEMBL30849632	0.72	HPRT1 (0.44)	ESR2RAB9ANPC1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.