SCHEMBL173527

SCHEMBL173527

N=C(Nc1cccc(F)c1)Nc1cccc(F)c1

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.60
KMT2A Q03164 5/20 0.60
IDO1 P14902 1/20 0.56
RAB9A P51151 3/20 0.55
TSHR P16473 1/20 0.55
NPC1 O15118 1/20 0.55
HPGD P15428 1/20 0.55
MAPT P10636 3/20 0.51
GAA P10253 3/20 0.51
HTT P42858 1/20 0.51
GFER P55789 1/20 0.51
ALDH1A1 P00352 2/20 0.50
TRPV1 Q8NER1 1/20 0.49
KDM4E B2RXH2 1/20 0.49
POLB P06746 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30753398 1.00 MEN1 (0.60) MEN1KMT2AIDO1RAB9ATSHR
SCHEMBL8867312 0.88 IDO1 (0.64) MEN1KMT2AIDO1RAB9ATSHR
SCHEMBL4100442 0.85 IDO1 (0.51) MEN1KMT2AIDO1RAB9ATSHR
Hydrochloric Acid SCHEMBL16702701 0.84 IDO1 (0.50) MEN1KMT2AIDO1RAB9ATSHR
SCHEMBL4678382 0.84 MEN1 (0.49) MEN1KMT2AIDO1RAB9ATSHR
SCHEMBL3443268 0.83 IDO1 (0.58) MEN1KMT2AIDO1RAB9ATSHR
SCHEMBL7873172 0.83 MEN1 (0.56) MEN1KMT2AIDO1RAB9ATSHR
SCHEMBL4100438 0.82 MEN1 (0.56) MEN1KMT2AIDO1RAB9ATSHR
SCHEMBL28014773 0.82 MEN1 (0.55) MEN1KMT2AIDO1RAB9ATSHR
SCHEMBL27111133 0.80 MEN1 (0.53) MEN1KMT2AIDO1RAB9ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11559763-B2 Regenerable solvent mixtures for acid-gas separation RESEARCH TRIANGLE INSTITUTE (US) 2023-01-24 US claimed
US-20260007998-A1 REGENERABLE SOLVENT MIXTURES FOR ACID-GAS SEPARATION RES TRIANGLE INST (US) 2026-01-08 US disclosed
US-12427471-B2 Regenerable solvent mixtures for acid-gas separation RESEARCH TRIANGLE INSTITUTE (NC) 2025-09-30 US disclosed
EP-4359111-A1 MBZA/PEG ETHYL ETHER BASED LIQUID SOLVENT CO2 CAPTURE IN ROTATING PACKED BED Research Triangle Institute (US) 2024-05-01 EP disclosed
US-20230241547-A1 REGENERABLE SOLVENT MIXTURES FOR ACID-GAS SEPARATION RES TRIANGLE INST (US) 2023-08-03 US disclosed
US-11612854-B2 Non-aqueous solvent CO2 capture in rotating packed bed RESEARCH TRIANGLE INSTITUTE (US) 2023-03-28 US disclosed
US-11559763-B2 Regenerable solvent mixtures for acid-gas separation RESEARCH TRIANGLE INSTITUTE (US) 2023-01-24 US disclosed
US-20220410063-A1 NON-AQUEOUS SOLVENT CO2 CAPTURE IN ROTATING PACKED BED RESEARCH TRIANGLE INSTITUTE 2022-12-29 US disclosed
WO-2022269546-A1 MBZA/PEG ETHYL ETHER BASED LIQUID SOLVENT CO2 CAPTURE IN ROTATING PACKED BED RESEARCH TRIANGLE INSTITUTE (US) 2022-12-29 WO disclosed
US-20210178316-A1 REGENERABLE SOLVENT MIXTURES FOR ACID-GAS SEPARATION RES TRIANGLE INST (US) 2021-06-17 US disclosed
US-10960345-B2 Regenerable solvent mixtures for acid-gas separation RESEARCH TRIANGLE INSTITUTE (NC) 2021-03-30 US disclosed
EP-2819767-B1 REGENERABLE SOLVENT MIXTURES FOR ACID-GAS SEPARATION RES TRIANGLE INST (US) 2019-09-11 EP disclosed
US-20180345206-A1 REGENERABLE SOLVENT MIXTURES FOR ACID-GAS SEPARATION RES TRIANGLE INST (US) 2018-12-06 US disclosed
US-10065148-B2 Regenerable solvent mixtures for acid-gas separation RESEARCH TRIANGLE INSTITUTE (US) 2018-09-04 US disclosed
US-9839875-B2 Regenerable solvent mixtures for acid-gas separation RESEARCH TRIANGLE INSTITUTE (US) 2017-12-12 US disclosed
EP-2611518-B1 REGENERABLE IONIC LIQUID SOLVENTS FOR ACID-GAS SEPARATION RES TRIANGLE INST (US) 2016-08-24 EP disclosed
US-20150328581-A1 REGENERABLE SOLVENT MIXTURES FOR ACID-GAS SEPARATION RES TRIANGLE INST (US) 2015-11-19 US disclosed
EP-2611518-A1 REGENERABLE IONIC LIQUID SOLVENTS FOR ACID -GAS SEPARATION Research Triangle Institute (US) 2013-07-10 EP disclosed
US-20130164199-A1 REGENERABLE SOLVENT MIXTURES FOR ACID-GAS SEPARATION RESEARCH TRIANGLE INSTITUTE 2013-06-27 US disclosed
WO-2012031274-A1 REGENERABLE IONIC LIQUID SOLVENTS FOR ACID -GAS SEPARATION RESEARCH TRIANGLE INSTITUTE (US) 2012-03-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260007998-A1 REGENERABLE SOLVENT MIXTURES FOR ACID-GAS SEPARATION NOS2, DUOX2, SMOX MEN1 2457/4885KMT2A 1553/4885IDO1 1153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.