Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL770492 | 0.86 | SMN1; SMN2 (0.45) | SMN1; SMN2NPC1RAB9AGAALMNA | |
| SCHEMBL17354072 | 0.84 | CALM1 (0.45) | SMN1; SMN2TAAR1F2RL1POLB | |
| SCHEMBL770265 | 0.84 | SMN1; SMN2 (0.43) | SMN1; SMN2NPC1RAB9AGAALMNA | |
| SCHEMBL6555269 | 0.83 | SMN1; SMN2 (0.49) | SMN1; SMN2NPC1RAB9AGAATAAR1 | |
| SCHEMBL17354078 | 0.78 | PPARA (0.34) | TAAR1F2RL1POLBGLS | |
| SCHEMBL17354073 | 0.78 | CYP1A2 (0.47) | SMN1; SMN2 | |
| SCHEMBL13789483 | 0.77 | ALPG (0.36) | SMN1; SMN2F2RL1LMNAPOLBGLS | |
| SCHEMBL16352360 | 0.76 | ALDH1A1 (0.48) | SMN1; SMN2GAALMNA | |
| SCHEMBL15806048 | 0.76 | RCE1 (0.35) | PTGS2 | |
| SCHEMBL12305405 | 0.74 | CALM1 (0.62) | SMN1; SMN2F2RL1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9217921-B2 | Resist underlayer film forming composition containing silicon having sulfide bond | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2015-12-22 | — | — | US | disclosed |