Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 2/20 | 0.34 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.32 |
| ▸ | BCR | P11274 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12593967 | 0.89 | KDM4E (0.38) | RXRAGRIN1GRIN2BNPSR1ABL1 | |
| SCHEMBL17354625 | 0.86 | RXRA (0.39) | RXRAGRIN1GRIN2BNPSR1ABL1 | |
| SCHEMBL17354613 | 0.83 | KDM4E (0.41) | MEN1KMT2AGPR3RAB9AKDM4E | |
| SCHEMBL9918761 | 0.80 | AR (0.45) | MEN1HTTKMT2AGPR3FFAR4 | |
| SCHEMBL17354618 | 0.79 | NPSR1 (0.38) | RXRAGRIN1GRIN2BNPSR1MEN1 | |
| SCHEMBL21581601 | 0.77 | DRD1 (0.40) | KMT2ADRD1GPR3RAB9AHAO1 | |
| SCHEMBL20650170 | 0.77 | GPR3 (0.46) | GRIN2BMEN1KMT2AGPR3FFAR4 | |
| SCHEMBL17536372 | 0.77 | MCHR1 (0.35) | RXRAGRIN1GRIN2BDRD1 | |
| SCHEMBL17571118 | 0.77 | XIAP (0.42) | ABL1MEN1KMT2A | |
| SCHEMBL30939555 | 0.76 | AR (0.45) | NPSR1MEN1KMT2ADRD1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9216967-B2 | Imidazolidinedione derivatives | AUTIFONY THERAPEUTICS LIMITED (GB) | 2015-12-22 | — | — | US | disclosed |