Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.54 |
| ▸ | AR | P10275 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5608759 | 0.88 | GAA (0.55) | ACHEARCA12CA1CA2 | |
| SCHEMBL14586639 | 0.88 | AR (0.51) | ACHEARTDP1LMNASMN1; SMN2 | |
| SCHEMBL7038743 | 0.86 | LTA4H (0.57) | ACHEARCA12CA1CA2 | |
| SCHEMBL1980701 | 0.85 | SMN1; SMN2 (0.58) | CA12CA1CA2CA7CA9 | |
| SCHEMBL14586634 | 0.84 | AR (0.62) | ACHEARCA12CA1CA2 | |
| SCHEMBL11786846 | 0.81 | ACHE (0.50) | ACHEARCA12CA1CA2 | |
| SCHEMBL22840074 | 0.81 | SLC6A4 (0.40) | ACHEARTDP1GAALMNA | |
| SCHEMBL29837419 | 0.81 | CA12 (0.65) | ACHECA12CA1CA2CA7 | |
| SCHEMBL140807 | 0.81 | CA12 (0.65) | ACHECA12CA1CA2CA7 | |
| SCHEMBL25012128 | 0.79 | ALDH1A1 (0.48) | ACHEARTDP1ALDH1A1TEAD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9216967-B2 | Imidazolidinedione derivatives | AUTIFONY THERAPEUTICS LIMITED (GB) | 2015-12-22 | — | — | US | disclosed |