SCHEMBL140807

SCHEMBL140807

COc1ccc(C)c(OC)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.65
CA1 P00915 2/20 0.65
CA2 P00918 2/20 0.65
CA7 P43166 2/20 0.65
CA9 Q16790 2/20 0.65
CA14 Q9ULX7 2/20 0.65
CYP1A1 P04798 8/20 0.56
CYP1A2 P05177 8/20 0.56
CYP1B1 Q16678 8/20 0.56
ALDH1A1 P00352 6/20 0.56
CYP3A4 P08684 3/20 0.56
MAPT P10636 3/20 0.50
CYP2E1 P05181 2/20 0.50
CYP2C8 P10632 2/20 0.50
CYP2D6 P10635 2/20 0.50
CYP2A6 P11509 2/20 0.50
CYP2C9 P11712 2/20 0.50
CYP4B1 P13584 2/20 0.50
CYP2B6 P20813 2/20 0.50
CYP3A5 P20815 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29837419 1.00 CA12 (0.65) CA12CA1CA2CA7CA9
Ammonia Solution, Strong SCHEMBL28752425 0.98 CA12 (0.62) CA12CA1CA2CA7CA9
SCHEMBL8035636 0.84 CA12 (0.46) CA12CA1CA2CA7CA9
SCHEMBL19886485 0.84 CA12 (0.46) CA12CA1CA2CA7CA9
SCHEMBL2002833 0.82 CA12 (0.50) CA12CA1CA2CA7CA9
SCHEMBL23052 0.82 CA12 (0.45) CA12CA1CA2CA7CA9
SCHEMBL29096230 0.82 CA12 (0.54) CA12CA1CA2CA7CA9
SCHEMBL14183054 0.81 CA12 (0.48) CA12CA1CA2CA7CA9
SCHEMBL12180454 0.81 CA12 (0.43) CA12CA1CA2CA7CA9
SCHEMBL13256249 0.81 NQO1 (0.50) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1529 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120000585-A Novel drug-assisted precursor micelle preparation and production method thereof 酰莱(合肥)生命科学研发有限公司 2025-05-16 CN claimed
CN-119999908-A Novel oil-soluble precursor micelle preparation and production method thereof 酰莱(合肥)生命科学研发有限公司 2025-05-16 CN claimed
EP-2595948-B1 A METHOD OF PRODUCING INGENOL-3-ANGELATE LEO LABORATORIES LTD (IE) 2019-09-04 EP claimed
US-10224485-B2 Process for preparing a crystalline organic semiconductor material BASF SE (DE) 2019-03-05 US claimed
EP-1915149-B1 NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS AETERNA ZENTARIS GMBH (DE) 2018-10-10 EP claimed
CN-108530273-A A kind of synthetic method of 2,4- dimethoxy-toluenes base -4- propyl diphenol 武汉桀升生物科技有限公司 2018-09-14 CN claimed
CN-107530259-A Method using acid amides, acid or ester C glycosides derivatives processing keratin material and the cosmetic composition containing them 莱雅公司 2018-01-02 CN claimed
CN-107011167-A The method for preparing the angelate of ingenol 3 利奥实验室有限公司 2017-08-04 CN claimed
US-20170001988-A1 PIPERIDINE AND PIPERAZINE DERIVATIVES AND THEIR USE IN TREATING VIRAL INFECTIONS AND CANCER THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 2017-01-05 US claimed
EP-3112352-A1 OPIOID RECEPTOR MODULATORS Janssen Pharmaceutica NV (BE) 2017-01-04 EP claimed
US-6992069-B2 Tricyclic macrolide antibacterial compounds ABBVIE INC. 2006-01-31 US claimed
US-20050234053-A1 9-oxo-3,4,6,9-tetrahydro-2H-[1,4]-(oxazino, thiazino, or pyrazino)[3,2-b][1,8]naphthyridine-8-carboxylic acids; fish or mammals; bacterial protein biosynthesis inhibitors ABBVIE INC. 2005-10-20 US claimed
WO-2005075477-A1 ANTIBACTERIAL COMPOUNDS ABBOTT LABORATORIES (US) 2005-08-18 WO claimed
US-20050159423-A1 Antibacterial compounds ABBOTT LABORATORIES 2005-07-21 US claimed
EP-1501846-A1 TRICYCLIC MACROLIDE ANTIBACTERIAL COMPOUNDS Abbott Laboratories (US) 2005-02-02 EP claimed
EP-1501797-A1 3-SUBSTITUTED AMINO-1H-INDOLE-2-CARBOXYLIC ACID AND 3-SUBSTITUTED AMINO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID DERIVATIVES AS INTERLEUKIN-4 GENE EXPRESSION INHIBITORS Aventis Pharmaceuticals, Inc. (US) 2005-02-02 EP claimed
EP-0986560-B1 PYRROLO 2,1,5-CD]INDOLIZINE DERIVATIVES USEFUL IN THE PREVENTION OR TREATMENT OF ESTROGEN RELATED DISEASES OR SYNDROMES KAROBIO AB (SE) 2004-03-24 EP claimed
US-20040029818-A1 Tricyclic macrolide antibacterial compounds ABBVIE INC. 2004-02-12 US claimed
WO-2003093289-A1 TRICYCLIC MACROLIDE ANTIBACTERIAL COMPOUNDS ABBOTT LABORATORIES (US) 2003-11-13 WO claimed
WO-2003091214-A1 3-SUBSTITUTED AMINO-1H-INDOLE-2-CARBOXYLIC ACID AND 3-SUBSTITUTED AMINO-BENZO AVENTIS PHARMACEUTICALS INC. (US) 2003-11-06 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170001988-A1 PIPERIDINE AND PIPERAZINE DERIVATIVES AND THEIR USE IN TREATING VIRAL INFECTIONS AND CANCER NCOR1, RRP15, NCOA1 CA12 1642/4885CA1 3196/4885CA2 3048/4885
US-20040029818-A1 Tricyclic macrolide antibacterial compounds RPN1, CASP1, MRPL21 CA12 4321/4885CA1 4144/4885CA2 3682/4885
US-20050159423-A1 Antibacterial compounds MRPL21, FDPS, PGLS CA12 4278/4885CA1 3427/4885CA2 2642/4885
US-10224485-B2 Process for preparing a crystalline organic semiconductor material STOM, SPOP, TTR CA12 299/4885CA1 140/4885CA2 458/4885
US-20050234053-A1 9-oxo-3,4,6,9-tetrahydro-2H-[1,4]-(oxazino, thiazino, or pyrazino)[3,2-b][1,8]naphthyridine-8-carboxylic acids; fish or mammals; bacterial protein biosynthesis inhibitors DHPS, COASY, PNPO CA12 4805/4885CA1 4449/4885CA2 2475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.