SCHEMBL17355706

SCHEMBL17355706

Cc1ccc(S(=O)(=O)Oc2ccc(Cl)c(C)c2)cc1

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.55
MEN1 O00255 2/20 0.55
APEX1 P27695 1/20 0.51
CA12 O43570 2/20 0.49
CA2 P00918 2/20 0.49
HTT P42858 3/20 0.48
ALDH1A1 P00352 3/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
MAPT P10636 2/20 0.48
HPGD P15428 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
ENPP3 O14638 1/20 0.48
ENPP1 P22413 1/20 0.48
ENPP2 Q13822 1/20 0.48
TDP1 Q9NUW8 2/20 0.45
LMNA P02545 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
ALPL P05186 3/20 0.44
ALPI P09923 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7249134 0.87 TDP1 (0.60) KMT2AMEN1APEX1CA12CA2
SCHEMBL6937983 0.85 MEN1 (0.59) KMT2AMEN1CA12CA2HTT
SCHEMBL11448636 0.82 APEX1 (0.50) KMT2AMEN1APEX1CA12CA2
SCHEMBL17352147 0.81 PLA2G7 (0.51) KMT2AMEN1APEX1CA12CA2
SCHEMBL8082103 0.81 MEN1 (0.55) KMT2AMEN1CA12CA2HTT
SCHEMBL17355689 0.81 KMT2A (0.55) KMT2AMEN1CA12CA2HTT
SCHEMBL9852204 0.80 MEN1 (0.60) KMT2AMEN1CA12CA2HTT
SCHEMBL18179825 0.80 MEN1 (0.60) KMT2AMEN1CA12CA2HTT
SCHEMBL4126086 0.80 MEN1 (0.60) KMT2AMEN1CA12CA2HTT
SCHEMBL11449208 0.80 ALPL (0.68) APEX1ALDH1A1ALPLALPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE UBE INDUSTRIES, LTD. (JP) 2015-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE HCN2, SCO2, HCN1 KMT2A 2355/4885MEN1 4646/4885APEX1 825/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.