Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.60 |
| ▸ | ALPL | P05186 | 3/20 | 0.53 |
| ▸ | ALPI | P09923 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.44 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17355706 | 0.87 | KMT2A (0.55) | TDP1ALPLALPIL3MBTL1SMN1; SMN2 | |
| SCHEMBL27978393 | 0.85 | TDP1 (0.66) | TDP1ALPLALPIMAOBL3MBTL1 | |
| SCHEMBL14341502 | 0.84 | APEX1 (0.55) | TDP1ALPLALPIMAOBL3MBTL1 | |
| SCHEMBL17355680 | 0.81 | TDP1 (0.56) | TDP1ALPLALPIMAOBL3MBTL1 | |
| SCHEMBL11448636 | 0.79 | APEX1 (0.50) | TDP1ALPLALPIL3MBTL1SMN1; SMN2 | |
| SCHEMBL6905828 | 0.78 | ALDH1A1 (0.49) | TDP1ALPLALPISMN1; SMN2APEX1 | |
| SCHEMBL17356398 | 0.77 | TDP1 (0.55) | TDP1ALPLALPIMAOBL3MBTL1 | |
| SCHEMBL7248921 | 0.77 | TDP1 (0.55) | TDP1ALPLALPIMAOBL3MBTL1 | |
| SCHEMBL11449208 | 0.77 | ALPL (0.68) | ALPLALPIAPEX1ALDH1A1 | |
| SCHEMBL11843404 | 0.76 | APEX1 (0.50) | TDP1ALPLALPIL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150372349-A1 | NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE | UBE INDUSTRIES, LTD. (JP) | 2015-12-24 | — | — | US | disclosed |
| US-6670388-B1 | Fatty acid synthase inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-12-30 | — | — | US | disclosed |
| WO-2002000620-A1 | FATTY ACID SYNTHASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150372349-A1 | NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE | HCN2, SCO2, HCN1 | TDP1 2884/4885ALPL 791/4885ALPI 1701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.