SCHEMBL17355707

SCHEMBL17355707

Cc1cc(F)cc(OS(C)(=O)=O)c1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.36
ALDH1A1 P00352 3/20 0.35
KDM4E B2RXH2 1/20 0.35
GAA P10253 1/20 0.35
EPAS1 Q99814 5/20 0.34
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
FFAR4 Q5NUL3 2/20 0.33
ALPL P05186 1/20 0.33
ALPI P09923 1/20 0.33
CA2 P00918 4/20 0.32
CA1 P00915 2/20 0.32
CA9 Q16790 2/20 0.32
CA12 O43570 2/20 0.32
PPARG P37231 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3738539 0.87 ALDH1A1 (0.39) HPGDALDH1A1KDM4EGAAEPAS1
SCHEMBL3845685 0.85 HPGD (0.41) HPGDALDH1A1KDM4EGAACYP3A4
SCHEMBL6941225 0.85 ALDH1A1 (0.44) HPGDALDH1A1KDM4EGAACYP3A4
SCHEMBL10204404 0.81 EPAS1 (0.37) EPAS1FFAR4CA2CA1
SCHEMBL9957670 0.80 ALDH1A1 (0.44) ALDH1A1GAAFFAR4CA2CA1
SCHEMBL8194919 0.78 ALDH1A1 (0.46) HPGDALDH1A1KDM4EGAACYP3A4
SCHEMBL8199185 0.76 ALPL (0.39) HPGDALDH1A1KDM4EGAACYP3A4
SCHEMBL17356310 0.76 SCN9A (0.37) ALDH1A1KDM4EEPAS1CA2CA1
SCHEMBL12871602 0.76 FABP3 (0.34) HPGDALDH1A1EPAS1
SCHEMBL15460152 0.76 IDH1 (0.38) HPGDALDH1A1KDM4EGAAEPAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE UBE INDUSTRIES, LTD. (JP) 2015-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE HCN2, SCO2, HCN1 HPGD 2190/4885ALDH1A1 1059/4885KDM4E 1067/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.