SCHEMBL17355709

SCHEMBL17355709

CS(=O)(=O)Oc1ccc(Cl)cc1C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 2/20 0.43
PROKR1 Q8TCW9 2/20 0.43
MRGPRX4 Q96LA9 4/20 0.42
PTGDR2 Q9Y5Y4 1/20 0.40
CCR2 P41597 3/20 0.39
SCN9A Q15858 1/20 0.39
HTR6 P50406 1/20 0.38
RAB9A P51151 2/20 0.38
PKM P14618 1/20 0.38
PPARG P37231 1/20 0.38
CYP1A2 P05177 2/20 0.38
CYP2C19 P33261 2/20 0.38
CYP2D6 P10635 1/20 0.38
HTT P42858 1/20 0.38
EPAS1 Q99814 1/20 0.37
TRPV4 Q9HBA0 1/20 0.37
CNR2 P34972 1/20 0.36
MEN1 O00255 1/20 0.36
POLB P06746 1/20 0.36
CYP3A4 P08684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15453964 0.81 RXRA (0.43) PTGDR2RAB9ACYP1A2CYP2C19MEN1
SCHEMBL17352156 0.81 MRGPRX4 (0.41) MRGPRX4SCN9AEPAS1
SCHEMBL16680513 0.77 PPARG (0.46) FPR2PROKR1MRGPRX4PTGDR2CCR2
SCHEMBL6059216 0.77 EPAS1 (0.37) FPR2PROKR1MRGPRX4CCR2SCN9A
SCHEMBL1875965 0.77 MAPT (0.48) RAB9ATRPV4POLBCYP2C9KMT2A
SCHEMBL13342828 0.75 TSHR (0.47) CYP1A2CYP2C19HTTTRPV4MEN1
SCHEMBL6941315 0.75 SLC22A12 (0.40) MRGPRX4PPARGMEN1KMT2A
SCHEMBL11119699 0.74 MRGPRX4 (0.44) MRGPRX4PTGDR2RAB9ACYP1A2CYP2C19
SCHEMBL14995469 0.74 KDM4E (0.46) PTGDR2HTTEPAS1TRPV4MEN1
SCHEMBL9145564 0.74 MAPT (0.49) CYP1A2CYP2C19CYP2D6HTTTRPV4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE UBE INDUSTRIES, LTD. (JP) 2015-12-24 US disclosed
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE UBE INDUSTRIES, LTD. (JP) 2015-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE HCN2, SCO2, HCN1 FPR2 2499/4885PROKR1 3386/4885MRGPRX4 4355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.