SCHEMBL17352156

SCHEMBL17352156

CS(=O)(=O)Oc1ccc(F)cc1C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 1/20 0.41
IDO1 P14902 2/20 0.40
SCN9A Q15858 1/20 0.38
KIF11 P52732 2/20 0.37
KDM4E B2RXH2 2/20 0.36
AR P10275 1/20 0.35
EPAS1 Q99814 1/20 0.35
BRD4 O60885 1/20 0.35
ALDH1A1 P00352 1/20 0.35
SLC6A4 P31645 1/20 0.35
HSD11B1 P28845 1/20 0.34
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17355695 0.86 KIF11 (0.41) IDO1KIF11KDM4EALDH1A1HSD11B1
SCHEMBL15453964 0.83 RXRA (0.43) KIF11KDM4EALDH1A1
SCHEMBL17355709 0.81 FPR2 (0.43) MRGPRX4SCN9AEPAS1
SCHEMBL6941315 0.80 SLC22A12 (0.40) MRGPRX4ALDH1A1HSD11B1
SCHEMBL3746820 0.78 PTGS2 (0.43) KDM4EEPAS1BRD4ALDH1A1SLC6A4
SCHEMBL9957765 0.77 KDM4E (0.49) KDM4EALDH1A1TSHR
SCHEMBL9024638 0.77 PTGS2 (0.42) MRGPRX4KDM4EALDH1A1SLC6A4TSHR
SCHEMBL17352142 0.76 KIF11 (0.37) IDO1KIF11
SCHEMBL13347573 0.76 NR3C2 (0.49) IDO1
SCHEMBL7164207 0.75 ALDH1A1 (0.43) SCN9AKDM4EALDH1A1SLC6A4HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE UBE INDUSTRIES, LTD. (JP) 2015-12-24 US claimed
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE UBE INDUSTRIES, LTD. (JP) 2015-12-24 US disclosed
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE UBE INDUSTRIES, LTD. (JP) 2015-12-24 US disclosed
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE UBE INDUSTRIES, LTD. (JP) 2015-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE HCN2, SCO2, HCN1 MRGPRX4 4355/4885IDO1 4571/4885SCN9A 172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.