SCHEMBL17356221

SCHEMBL17356221

Cc1ccc(/C=C/C(=O)c2ccc(O)cc2O)cc1O

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.76
KMT2A Q03164 6/20 0.76
NFKB1 P19838 4/20 0.76
NFKB2 Q00653 3/20 0.76
RELA Q04206 3/20 0.76
AKR1B1 P15121 2/20 0.76
HSD17B2 P37059 2/20 0.76
EGFR P00533 1/20 0.76
SRC P12931 1/20 0.76
CDK2 P24941 1/20 0.76
PIK3CA P42336 1/20 0.76
HDAC6 Q9UBN7 1/20 0.76
CYP3A4 P08684 5/20 0.72
TDP1 Q9NUW8 4/20 0.72
MAPT P10636 4/20 0.72
HPGD P15428 4/20 0.72
ALOX15 P16050 4/20 0.72
MAPK1 P28482 4/20 0.72
TP53 P04637 3/20 0.72
HSD17B10 Q99714 3/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30383541 1.00 MEN1 (0.76) MEN1KMT2ANFKB1NFKB2RELA
SCHEMBL31232994 0.91 MEN1 (0.72) MEN1KMT2ANFKB1NFKB2RELA
SCHEMBL15218642 0.91 MEN1 (0.72) MEN1KMT2ANFKB1NFKB2RELA
SCHEMBL17616945 0.88 MEN1 (0.76) MEN1KMT2ANFKB1NFKB2RELA
SCHEMBL30382794 0.88 MEN1 (0.76) MEN1KMT2ANFKB1NFKB2RELA
Butein SCHEMBL25202104 0.86 KMT2A (1.00) MEN1KMT2ANFKB1NFKB2RELA
Butein SCHEMBL139243 0.86 KMT2A (1.00) MEN1KMT2ANFKB1NFKB2RELA
Butein SCHEMBL243646 0.86 KMT2A (1.00) MEN1KMT2ANFKB1NFKB2RELA
Butein SCHEMBL243647 0.86 KMT2A (1.00) MEN1KMT2ANFKB1NFKB2RELA
Butein SCHEMBL29724857 0.86 KMT2A (1.00) MEN1KMT2ANFKB1NFKB2RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed
US-20150366206-A1 SELECTIVE INHIBITION OF C4-PEP CARBOXYLASES HEINRICH HEINE UNIVERSITÄT DÜSSELDORF (DE) 2015-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150366206-A1 SELECTIVE INHIBITION OF C4-PEP CARBOXYLASES PC, CPS1, ME1 MEN1 2751/4885KMT2A 2285/4885NFKB1 3209/4885
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MEN1 3367/4885KMT2A 2792/4885NFKB1 1669/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MEN1 2457/4885KMT2A 3188/4885NFKB1 2437/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MEN1 2457/4885KMT2A 3188/4885NFKB1 2437/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.