SCHEMBL17359379

SCHEMBL17359379

FC(F)(F)c1ccc(N2c3ccc(C(F)(F)F)cc3Sc3cc(C(F)(F)F)ccc32)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN5 P54829 1/20 0.40
CYBB P04839 1/20 0.40
NOX3 Q9HBY0 1/20 0.40
NOX4 Q9NPH5 1/20 0.40
NOX1 Q9Y5S8 1/20 0.40
ALDH1A1 P00352 3/20 0.40
PKM P14618 1/20 0.40
HDAC6 Q9UBN7 2/20 0.37
TP53 P04637 2/20 0.36
NPC1 O15118 1/20 0.36
ABCB11 O95342 1/20 0.36
CYP1A2 P05177 1/20 0.36
CHRM2 P08172 1/20 0.36
ABCB1 P08183 1/20 0.36
HTR1A P08908 1/20 0.36
ADRA2A P08913 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
CYP2D6 P10635 1/20 0.36
CHRM1 P11229 1/20 0.36
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17356872 0.91 MEN1 (0.40) PTPN5CYBBNOX3NOX4NOX1
SCHEMBL21402681 0.90 KIF11 (0.39) CYBBNOX3NOX4NOX1ALDH1A1
SCHEMBL17359361 0.90 LMNA (0.39) PTPN5CYBBNOX3NOX4NOX1
SCHEMBL17356844 0.90 GSK3A (0.36) PTPN5CYBBNOX3NOX4NOX1
SCHEMBL17359374 0.89 CYBB (0.45) PTPN5CYBBNOX3NOX4NOX1
SCHEMBL17359351 0.86 CFTR (0.34) PTPN5CYBBNOX3NOX4NOX1
SCHEMBL17682028 0.84 HDAC6 (0.54) CYBBNOX3NOX4NOX1ALDH1A1
SCHEMBL29617994 0.84 HDAC6 (0.54) CYBBNOX3NOX4NOX1ALDH1A1
SCHEMBL17359362 0.82 CYBB (0.38) PTPN5CYBBNOX3NOX4NOX1
SCHEMBL17359372 0.80 HDAC6 (0.45) ALDH1A1HDAC6TSHRLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150372333-A1 NON-AQUEOUS REDOX FLOW BATTERIES INCLUDING 3,7-PERFLUOROALKYLATED PHENOTHIAZINE DERIVATIVES UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION 2015-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150372333-A1 NON-AQUEOUS REDOX FLOW BATTERIES INCLUDING 3,7-PERFLUOROALKYLATED PHENOTHIAZINE DERIVATIVES GPX4, VDAC3, AQP1 PTPN5 192/4885CYBB 701/4885NOX3 530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.