Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 8/20 | 0.53 |
| ▸ | LPL | P06858 | 2/20 | 0.49 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.49 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1723229 | 0.82 | ENPP2 (0.60) | ENPP2LPLLIPGCXCR1CXCR2 | |
| SCHEMBL19492821 | 0.79 | ENPP2 (0.56) | ENPP2LPLLIPGCXCR1CXCR2 | |
| SCHEMBL6353060 | 0.78 | ENPP2 (0.55) | ENPP2LPLLIPGKDM4EALDH1A1 | |
| SCHEMBL29956793 | 0.76 | ENPP2 (0.52) | ENPP2LPLLIPGCXCR1CXCR2 | |
| SCHEMBL29951479 | 0.76 | ENPP2 (0.49) | ENPP2LPLLIPG | |
| SCHEMBL8528 | 0.75 | ENPP2 (0.61) | ENPP2LPLLIPGKDM4EALDH1A1 | |
| SCHEMBL28413768 | 0.75 | ENPP2 (0.55) | ENPP2LPLLIPGCXCR1CXCR2 | |
| SCHEMBL2562738 | 0.74 | LPL (0.54) | ENPP2LPLLIPGKDM4EALDH1A1 | |
| SCHEMBL2634549 | 0.74 | ENPP2 (0.50) | ENPP2LPLLIPGCXCR1CXCR2 | |
| SCHEMBL29953749 | 0.73 | ENPP2 (0.49) | ENPP2LPLLIPGCXCR1CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9220711-B2 | Compounds for the treatment of pathologies associated with aging and degenerative disorders | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2015-12-29 | — | — | US | disclosed |