Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 5/20 | 0.49 |
| ▸ | LPL | P06858 | 2/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6353060 | 0.87 | ENPP2 (0.55) | ENPP2LPLLIPGKDM4ESMN1; SMN2 | |
| SCHEMBL29955815 | 0.85 | CHRNB2 (0.62) | ENPP2LPLLIPGCHRNB2CHRNA4 | |
| SCHEMBL29954574 | 0.82 | LPL (0.47) | LPLLIPGCHRNB2CHRNA4CXCR1 | |
| SCHEMBL19492821 | 0.82 | ENPP2 (0.56) | ENPP2LPLLIPGCHRNB2CHRNA4 | |
| SCHEMBL29954447 | 0.80 | CYP2D6 (0.52) | ENPP2LPLLIPGCXCR1CXCR2 | |
| SCHEMBL1723229 | 0.79 | ENPP2 (0.60) | ENPP2LPLLIPGCHRNB2CHRNA4 | |
| SCHEMBL27947483 | 0.76 | SMN1; SMN2 (0.50) | CHRNB2CHRNA4KDM4ESMN1; SMN2CYP1A2 | |
| SCHEMBL28413768 | 0.74 | ENPP2 (0.55) | ENPP2LPLLIPGCXCR1CXCR2 | |
| SCHEMBL30093206 | 0.74 | KDM4E (0.53) | CHRNB2CHRNA4KDM4ESMN1; SMN2CYP1A2 | |
| SCHEMBL29957724 | 0.74 | KDM4E (0.43) | LIPGCHRNB2CHRNA4CXCR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |