Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | PDE1A | P54750 | 6/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 6/20 | 0.34 |
| ▸ | PDE1C | Q14123 | 6/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1736873 | 0.99 | HTR6 (0.34) | HTR6DPP4PLA2G2APDE1APDE1B | |
| SCHEMBL1739772 | 0.94 | FABP4 (0.38) | HTR6MEN1KMT2AHSD17B10MAPT | |
| SCHEMBL1737566 | 0.94 | HTR6 (0.35) | HTR6DPP4PLA2G2APDE1APDE1B | |
| SCHEMBL1737665 | 0.93 | HTR6 (0.35) | HTR6DPP4PLA2G2APDE1APDE1B | |
| Hydrochloric Acid SCHEMBL1738233 | 0.93 | FABP4 (0.37) | HTR6MEN1KMT2AHSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL1737036 | 0.93 | HTR6 (0.35) | HTR6DPP4PLA2G2APDE1APDE1B | |
| SCHEMBL1738012 | 0.93 | FABP4 (0.35) | HTR6DPP4PLA2G2APDE1APDE1B | |
| Hydrochloric Acid SCHEMBL1737491 | 0.93 | HTR6 (0.34) | HTR6DPP4PLA2G2APDE1APDE1B | |
| Hydrochloric Acid SCHEMBL1736728 | 0.92 | FABP4 (0.35) | HTR6DPP4PLA2G2APDE1APDE1B | |
| SCHEMBL1736826 | 0.92 | CYP2D6 (0.37) | HTR6PLA2G2AMEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | claimed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | claimed |