SCHEMBL1738012

SCHEMBL1738012

Cc1c(C)n(Cc2cccc(F)c2)c2c(N3CCc4ccccc4C3C)nccc12

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 2/20 0.35
DPP4 P27487 1/20 0.34
PLA2G2A P14555 1/20 0.34
FABP3 P05413 1/20 0.34
PDE1A P54750 4/20 0.34
PDE1B Q01064 4/20 0.34
PDE1C Q14123 4/20 0.34
HTR2A P28223 3/20 0.34
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
KMT2A Q03164 1/20 0.34
HSD17B10 Q99714 1/20 0.34
HTR2C P28335 1/20 0.34
HTR2B P41595 1/20 0.34
ENPP2 Q13822 3/20 0.34
HTR6 P50406 3/20 0.33
HTR1A P08908 2/20 0.33
DRD2 P14416 2/20 0.33
HTR7 P34969 2/20 0.33
CACNA1G O43497 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1736728 0.99 FABP4 (0.35) FABP4DPP4PLA2G2AFABP3PDE1A
SCHEMBL1737566 0.94 HTR6 (0.35) FABP4DPP4PLA2G2APDE1APDE1B
Hydrochloric Acid SCHEMBL1737036 0.93 HTR6 (0.35) FABP4DPP4PLA2G2APDE1APDE1B
SCHEMBL1736043 0.93 HTR6 (0.35) FABP4DPP4PLA2G2APDE1APDE1B
Hydrochloric Acid SCHEMBL1736873 0.92 HTR6 (0.34) FABP4DPP4PLA2G2APDE1APDE1B
SCHEMBL1737624 0.90 HTR2A (0.35) FABP4DPP4PLA2G2APDE1APDE1B
SCHEMBL1737790 0.90 FABP4 (0.42) FABP4MEN1ALDH1A1KMT2AHSD17B10
SCHEMBL1737665 0.90 HTR6 (0.35) FABP4DPP4PLA2G2APDE1APDE1B
Hydrochloric Acid SCHEMBL1737690 0.90 HTR2A (0.34) FABP4DPP4PLA2G2APDE1APDE1B
Hydrochloric Acid SCHEMBL1737491 0.89 HTR6 (0.34) FABP4DPP4PLA2G2APDE1APDE1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1784404-B1 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORP (KR) 2011-11-16 EP claimed
US-20110263306-A1 COMPUTER SYSTEM AND PROGRAM NAMCO BANDAI GAMES INC. (JP) 2011-10-27 US claimed
EP-1784404-A4 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORP (KR) 2009-09-09 EP disclosed
EP-1784404-A1 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF Yuhan Corporation (KR) 2007-05-16 EP disclosed
WO-2006025716-A1 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORPORATION (KR) 2006-03-09 WO disclosed