Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25403651 | 0.86 | — | — | |
| SCHEMBL147085 | 0.84 | CYP2C19 (0.54) | GPR55TDP1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL31738884 | 0.84 | CYP2C19 (0.54) | GPR55TDP1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6229874 | 0.83 | CALM1 (0.58) | MEN1KMT2AHPGDHTR2A | |
| SCHEMBL7918865 | 0.82 | CYP2C19 (0.52) | GPR55TDP1CYP1A2CYP2C9CYP2C19 | |
| Hydrogen Sulfide SCHEMBL28838423 | 0.82 | CYP2C19 (0.52) | GPR55TDP1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7918863 | 0.82 | CYP2C19 (0.52) | GPR55TDP1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29040201 | 0.81 | CALM1 (0.55) | MEN1KMT2AHPGDHTR2A | |
| SCHEMBL29111442 | 0.80 | GPR55 (0.44) | GPR55 | |
| Methane SCHEMBL27919160 | 0.80 | CYP2C19 (0.50) | GPR55TDP1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170143763-A1 | ORALLY ADMINISTERED ADSORBENT, THERAPEUTIC AGENT FOR RENAL DISEASE, AND THERAPEUTIC AGENT FOR LIVER DISEASE | KUREHA CORPORATION (JP) | 2017-05-25 | — | — | US | disclosed |
| US-20160000827-A1 | ORALLY ADMINISTERED ADSORBENT, THERAPEUTIC AGENT FOR RENAL DISEASE, AND THERAPEUTIC AGENT FOR LIVER DISEASE | KUREHA CORPORATION (JP) | 2016-01-07 | — | — | US | disclosed |
| US-20150374743-A1 | ORALLY ADMINISTERED ADSORBENT, THERAPEUTIC AGENT FOR RENAL DISEASE, AND THERAPEUTIC AGENT FOR LIVER DISEASE | KUREHA CORPORATION (JP) | 2015-12-31 | — | — | US | disclosed |
| EP-2959906-A1 | ORALLY ADMINISTERED ADSORBENT, THERAPEUTIC AGENT FOR RENAL DISEASE, AND THERAPEUTIC AGENT FOR LIVER DISEASE | Kureha Corporation (JP) | 2015-12-30 | — | — | EP | disclosed |
| EP-2959905-A1 | ORALLY ADMINISTERED ADSORBENT, THERAPEUTIC AGENT FOR RENAL DISEASE, AND THERAPEUTIC AGENT FOR LIVER DISEASE | Kureha Corporation (JP) | 2015-12-30 | — | — | EP | disclosed |