Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.41 |
| ▸ | TUBB | P07437 | 2/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3967129 | 0.84 | CES2 (0.49) | PRNPTSHRMAPK1PPARGHTT | |
| SCHEMBL5089818 | 0.84 | TSHR (0.45) | PRNPTSHRMAPK1PPARGHTT | |
| SCHEMBL6832588 | 0.80 | TUBB4A (0.57) | PRNPTSHRMAPK1PPARGHTT | |
| SCHEMBL20425283 | 0.77 | TUBB4A (0.51) | PRNPTSHRMAPK1PPARGHTT | |
| SCHEMBL15954746 | 0.77 | TUBB4A (0.48) | PRNPTSHRMAPK1PPARGHTT | |
| SCHEMBL21176572 | 0.77 | TUBB4A (0.42) | PRNPTSHRMAPK1PPARGHTT | |
| SCHEMBL10369463 | 0.77 | CA2 (0.52) | PRNPTSHRMAPK1PPARGHTT | |
| SCHEMBL30610956 | 0.77 | TUBB4A (0.51) | PRNPTSHRMAPK1PPARGHTT | |
| SCHEMBL10031374 | 0.76 | HTT (0.51) | PRNPTSHRMAPK1PPARGHTT | |
| SCHEMBL7107022 | 0.76 | L3MBTL1 (0.49) | PRNPTSHRMAPK1PPARGHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2958907-A1 | BENZOTHIOPHENE DERIVATIVES AND COMPOSITIONS THEREOF AS SELECTIVE ESTROGEN RECEPTOR DEGRADERS | Novartis AG (CH) | 2015-12-30 | — | — | EP | disclosed |