Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL322525 | 0.77 | LMNA (0.40) | TSHRHSD17B10KDM4EMEN1LMNA | |
| SCHEMBL10444174 | 0.77 | KDM4E (0.45) | ALOX15TSHRHSD17B10KDM4EMEN1 | |
| SCHEMBL875632 | 0.71 | ALOX15 (0.57) | ALOX15TSHRHSD17B10KDM4ETP53 | |
| SCHEMBL11067870 | 0.71 | ALOX15 (0.62) | ALOX15TSHRHSD17B10KDM4ETP53 | |
| SCHEMBL1001721 | 0.70 | RXRA (0.42) | HSD17B10KDM4EMEN1LMNATTR | |
| SCHEMBL7258244 | 0.70 | KDM4E (0.36) | TSHRKDM4EMEN1LMNATTR | |
| SCHEMBL8603982 | 0.70 | KMT2A (0.41) | ALOX15TSHRHSD17B10KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL12468468 | 0.70 | ALOX15 (0.56) | ALOX15TSHRHSD17B10KDM4ETP53 | |
| SCHEMBL10443829 | 0.69 | SRD5A1 (0.59) | HSD17B10KDM4EMEN1LMNAMAPT | |
| SCHEMBL5052560 | 0.69 | TPMT (0.50) | ALOX15TSHRHSD17B10KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2764004-B1 | METHOD FOR THE PREPARATION OF METAL ORGANIC FRAMEWORKS | FUNDACIÓ INST CATALÀ DE NANOCIÈNCIA I NANOTECNOLOGIA (ES) | 2015-12-30 | — | — | EP | claimed |