Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PRKCA | P17252 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.35 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | KDM5C | P41229 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.35 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11437280 | 0.91 | LMNA (0.45) | LMNAPRKCAALDH1A1EGLN1KDM6B | |
| SCHEMBL1473026 | 0.81 | PRKCA (0.43) | LMNAPRKCAALDH1A1 | |
| SCHEMBL14899785 | 0.76 | PRKCA (0.40) | PRKCAALDH1A1CYP2C19 | |
| SCHEMBL8444652 | 0.73 | PRKCA (0.45) | PRKCAALDH1A1 | |
| SCHEMBL18039599 | 0.72 | TSHR (0.41) | LMNAPRKCAALDH1A1EGLN1KDM6B | |
| SCHEMBL28625576 | 0.71 | ALOX15 (0.37) | LMNACYP2C19 | |
| SCHEMBL1237232 | 0.69 | LMNA (0.50) | LMNAALDH1A1EGLN1KDM6BKDM5C | |
| SCHEMBL8520271 | 0.69 | LMNA (0.41) | LMNAPRKCAALDH1A1 | |
| SCHEMBL2336160 | 0.69 | LMNA (0.56) | LMNAALDH1A1EGLN1KDM6BKDM5C | |
| Succinic Acid SCHEMBL11437283 | 0.69 | LMNA (0.48) | LMNAALDH1A1EGLN1KDM6BKDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2960233-A1 | NEW THERAPEUTIC AGENTS | Cancer Research Technology Limited (GB) | 2015-12-30 | — | — | EP | disclosed |