Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | PAM | P19021 | 2/20 | 0.40 |
| ▸ | PRKCA | P17252 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1473026 | 0.90 | PRKCA (0.43) | LMNATSHRNFKB1PMP22PAM | |
| SCHEMBL28325451 | 0.89 | TSHR (0.42) | TSHRPAMPRKCAALDH1A1 | |
| SCHEMBL8418026 | 0.85 | DGKA (0.55) | TSHRPAMPRKCA | |
| SCHEMBL28160821 | 0.85 | PAM (0.44) | TSHRPAMPRKCAALDH1A1 | |
| SCHEMBL17026000 | 0.81 | PRKCA (0.39) | LMNATSHRPRKCAALDH1A1 | |
| SCHEMBL3095096 | 0.81 | PRKCA (0.34) | LMNATSHRPRKCAUSP2ALDH1A1 | |
| SCHEMBL11437280 | 0.79 | LMNA (0.45) | LMNATSHRPRKCAUSP2ALDH1A1 | |
| SCHEMBL258590 | 0.77 | LMNA (0.33) | LMNATSHRPRKCAUSP2ALDH1A1 | |
| SCHEMBL9861918 | 0.76 | TSHR (0.50) | LMNATSHRNFKB1PMP22USP2 | |
| SCHEMBL11818895 | 0.75 | PRKCA (0.43) | TSHRPAMPRKCAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659789-B1 | Polyurethane composition for use as a dispersing binder | GOODRICH CO B F (US) | 1999-07-07 | — | — | EP | disclosed |
| EP-0659789-A1 | Polyurethane composition for use as a dispersing binder | THE B.F. GOODRICH COMPANY (US) | 1995-06-28 | — | — | EP | disclosed |
| US-5371166-A | High gloss, hydrolytic stability, magnetic recording media | THE B. F. GOODRICH COMPANY (US) | 1994-12-06 | — | — | US | disclosed |