Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 7/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL347489 | 0.81 | ALOX15 (0.66) | ALOX15ALOX12HPGDCES2GALR3 | |
| SCHEMBL30688242 | 0.81 | ALOX15 (0.66) | ALOX15ALOX12HPGDCES2GALR3 | |
| SCHEMBL74689 | 0.77 | MAOB (0.61) | ALOX15ALOX12HPGDMEN1HTT | |
| SCHEMBL29744489 | 0.77 | MAOB (0.61) | ALOX15ALOX12HPGDMEN1HTT | |
| SCHEMBL282961 | 0.72 | ALDH1A1 (0.56) | ALOX15ALOX12HPGDMEN1LMNA | |
| SCHEMBL129673 | 0.72 | AR (0.49) | ALOX15ALOX12HPGDCES2GALR3 | |
| SCHEMBL213780 | 0.72 | MAOA (0.49) | ALOX15ALOX12HPGDCES2GALR3 | |
| SCHEMBL128318 | 0.71 | ALOX15 (0.46) | ALOX15ALOX12HPGDCES2GALR3 | |
| Bromide SCHEMBL5574020 | 0.71 | MAOA (0.48) | ALOX15ALOX12HPGDCES2GALR3 | |
| SCHEMBL5951224 | 0.71 | ALOX15 (0.54) | ALOX15ALOX12HPGDMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588451-B1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INT (DE) | 2015-12-30 | — | — | EP | disclosed |