SCHEMBL347489

SCHEMBL347489

Oc1ccc(Br)cc1Oc1cc(Br)ccc1O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 8/20 0.66
ALOX12 P18054 3/20 0.66
HPGD P15428 2/20 0.55
MEN1 O00255 1/20 0.55
LMNA P02545 1/20 0.55
MAPT P10636 1/20 0.55
HTT P42858 1/20 0.55
KMT2A Q03164 1/20 0.55
ATM Q13315 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
MAPK1 P28482 2/20 0.52
ALDH1A1 P00352 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
CES2 O00748 1/20 0.46
GALR3 O60755 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
CASP1 P29466 1/20 0.46
CYP2C19 P33261 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30688242 1.00 ALOX15 (0.66) ALOX15ALOX12HPGDMEN1LMNA
SCHEMBL5951224 0.83 ALOX15 (0.54) ALOX15ALOX12HPGDMEN1LMNA
SCHEMBL74689 0.81 MAOB (0.61) ALOX15ALOX12HPGDMEN1HTT
SCHEMBL29744489 0.81 MAOB (0.61) ALOX15ALOX12HPGDMEN1HTT
SCHEMBL17366241 0.81 ALOX15 (0.52) ALOX15ALOX12HPGDMEN1LMNA
SCHEMBL46705 0.79 TTR (0.47) ALOX15ALOX12HPGDMEN1LMNA
SCHEMBL20550743 0.79 ALOX15 (0.76) ALOX15ALOX12HPGDMEN1LMNA
SCHEMBL13580946 0.76 ALOX15 (0.47) ALOX15ALOX12HPGDMEN1LMNA
SCHEMBL282961 0.76 ALDH1A1 (0.56) ALOX15ALOX12HPGDMEN1LMNA
SCHEMBL129673 0.76 AR (0.49) ALOX15ALOX12HPGDMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 942 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11185480-B2 Buffered microencapsulated compositions and methods PREMIER DENTAL PRODUCTS COMPANY (US) 2021-11-30 US claimed
EP-3765036-A1 BUFFERED MICROENCAPSULATED COMPOSITIONS AND METHODS Premier Dental Products Company (US) 2021-01-20 EP claimed
US-10688026-B2 Buffered microencapsulated compositions and methods PREMIER DENTAL PRODUCTS COMPANY (US) 2020-06-23 US claimed
US-20200016051-A1 BUFFERED MICROENCAPSULATED COMPOSITIONS AND METHODS FIDELITY DIRECT LENDING LLC, AS ADMINISTRATIVE AGENT 2020-01-16 US claimed
WO-2019177927-A1 BUFFERED MICROENCAPSULATED COMPOSITIONS AND METHODS PREMIER DENTAL PRODUCTS COMPANY (US) 2019-09-19 WO claimed
US-20190099335-A1 BUFFERED MICROENCAPSULATED COMPOSITIONS AND METHODS PREMIER DENTAL PRODUCTS COMPANY 2019-04-04 US claimed
US-20180200164-A1 BUFFERED MICROENCAPSULATED COMPOSITIONS AND METHODS FIDELITY DIRECT LENDING LLC, AS ADMINISTRATIVE AGENT 2018-07-19 US claimed
EP-2152845-B1 HARD SURFACE CLEANING COMPOSITION WITH HYDROPHILIZING AGENT AND METHOD FOR CLEANING HARD SURFACES SOLVAY USA INC (US) 2017-03-29 EP claimed
US-20150335557-A1 ANTI-PLAQUE ORAL COMPOSITIONS BHUSNAN RAJIV (US) 2015-11-26 US claimed
EP-2934694-A1 ANTI-PLAQUE ORAL COMPOSITIONS Bhushan, Rajiv (US) 2015-10-28 EP claimed
WO-2003089561-A2 COMPOSITIONS COMPRISING A DISPERSANT AND MICROCAPSULES CONTAINING AN ACTIVE MATERIAL THE PROCTER & GAMBLE COMPANY (US) 2003-10-30 WO claimed
US-6616922-B2 For use in cleansing formulations to cleasne the skin and to destroy bacteria and other microorganisms present on the skin, especially the hands, arms, and face of the user THE DIAL CORPORATION 2003-09-09 US claimed
US-20030022941-A1 For use in cleansing formulations to cleasne the skin and to destroy bacteria and other microorganisms present on the skin, especially the hands, arms, and face of the user Henkel IP & Holding GmbH (DE) 2003-01-30 US claimed
US-20020090349-A1 Process for the biocidal treatment of surface BERGERON VANCE (FR) 2002-07-11 US claimed
WO-2001093820-A1 ANTIPLAQUE AQUEOUS ORAL COMPOSITION RHODIA CHIMIE (FR) 2001-12-13 WO claimed
US-5665333-A Methods, compositions, and dental delivery systems for the protection of the surfaces of teeth PROVSEAL LLC 1997-09-09 US claimed
US-5279813-A Solid polyethylene or polyethyleneterephthalate COLGATE-PALMOLIVE COMPANY (US) 1994-01-18 US claimed
US-5273741-A Bactericide of water-insoluble noncationic halogenated diphenyl ether and stabilizer in a compatible dispenser of polyethylene or polyethylene terephthalate COLGATE-PALMOLIVE COMPANY (US) 1993-12-28 US claimed
US-5167951-A Stabilizer of halogenated diphenyl ether bactericide COLGATE-PALMOLIVE COMPANY (US) 1992-12-01 US claimed
US-5135738-A Polyethylene or PET dispenser with halogenated diphenyl ether bactericide and stabilizer COLGATE-PALMOLIVE COMPANY (US) 1992-08-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10688026-B2 Buffered microencapsulated compositions and methods LIPA, CHMP4B, APOB ALOX15 860/4885ALOX12 1164/4885HPGD 2041/4885
US-11185480-B2 Buffered microencapsulated compositions and methods CHMP4B, LIPA, APOB ALOX15 1317/4885ALOX12 1765/4885HPGD 2167/4885
US-20150335557-A1 ANTI-PLAQUE ORAL COMPOSITIONS MGMT, CAPG, TRPM7 ALOX15 4346/4885ALOX12 4049/4885HPGD 1333/4885
US-20180200164-A1 BUFFERED MICROENCAPSULATED COMPOSITIONS AND METHODS LIPA, CHMP4B, APOB ALOX15 860/4885ALOX12 1164/4885HPGD 2041/4885
US-20030022941-A1 For use in cleansing formulations to cleasne the skin and to destroy bacteria and other microorganisms present on the skin, especially the hands, arms, and face of the user CUTA, CHIT1, CLSPN ALOX15 496/4885ALOX12 285/4885HPGD 3810/4885
US-20200016051-A1 BUFFERED MICROENCAPSULATED COMPOSITIONS AND METHODS CHMP4B, LIPA, APOB ALOX15 1317/4885ALOX12 1765/4885HPGD 2167/4885
US-20190099335-A1 BUFFERED MICROENCAPSULATED COMPOSITIONS AND METHODS LIPA, CHMP4B, APOB ALOX15 1153/4885ALOX12 1541/4885HPGD 1924/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.