Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.61 |
| ▸ | NAMPT | P43490 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | STS | P08842 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | JAK1 | P23458 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CCR1 | P32246 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8040438 | 0.85 | NAMPT (0.54) | GPR119NAMPTSMN1; SMN2KDM4EGAA | |
| SCHEMBL17360240 | 0.85 | KMT2A (0.55) | GPR119SMN1; SMN2GAATHRBNPC1 | |
| SCHEMBL22193619 | 0.84 | PRMT5 (0.61) | GPR119NAMPTSMN1; SMN2KDM4EPKM | |
| SCHEMBL14824682 | 0.84 | NAMPT (0.65) | GPR119NAMPTSMN1; SMN2STSGAA | |
| SCHEMBL31198857 | 0.84 | GPR119 (0.57) | GPR119NAMPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL28044746 | 0.83 | LMNA (0.48) | GPR119GAATHRBRAB9AHTT | |
| SCHEMBL1857852 | 0.83 | GPR119 (0.53) | GPR119SMN1; SMN2KDM4EPKMSTS | |
| SCHEMBL31701852 | 0.83 | NAMPT (0.51) | GPR119NAMPTSMN1; SMN2KDM4EPKM | |
| SCHEMBL1852189 | 0.83 | KDM4E (0.59) | GPR119KDM4EPKMSTSHTT | |
| SCHEMBL944418 | 0.83 | GPR119 (0.57) | GPR119KDM4EPKMSTS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240294497-A1 | METHOD FOR PRODUCING MONOCYCLIC PYRIDINE DERIVATIVE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2024-09-05 | — | — | US | disclosed |
| EP-4361143-A1 | METHOD FOR PRODUCING MONOCYCLIC PYRIDINE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2024-05-01 | — | — | EP | disclosed |
| CN-117715902-A | Process for producing monocyclic pyridine derivative | 卫材R&D管理有限公司 | 2024-03-15 | — | — | CN | disclosed |
| EP-2960238-B1 | MONOCYCLIC PYRIDINE DERIVATIVE | EISAI R&D MAN CO LTD (JP) | 2017-04-05 | — | — | EP | disclosed |
| EP-2960238-A1 | MONOCYCLIC PYRIDINE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2015-12-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240294497-A1 | METHOD FOR PRODUCING MONOCYCLIC PYRIDINE DERIVATIVE | BRD7, SIRT7, PRDM7 | GPR119 3235/4885NAMPT 122/4885SMN1; SMN2 2498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.