Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.43 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28011843 | 0.85 | FDFT1 (0.51) | LMNATDP1MAPTALDH1A1HPGD | |
| SCHEMBL17366247 | 0.83 | GPR119 (0.61) | LMNAGPR119CCR1GAARAB9A | |
| SCHEMBL27488566 | 0.82 | RIPK1 (0.51) | ALDH1A1L3MBTL1SLC18A3 | |
| SCHEMBL17360240 | 0.81 | KMT2A (0.55) | LMNAKMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL27812545 | 0.81 | HSD17B10 (0.45) | TDP1MAPTALDH1A1HPGDGAA | |
| SCHEMBL28174922 | 0.80 | TDP1 (0.50) | LMNAKMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL29198620 | 0.78 | KMT2A (0.46) | LMNAKMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL29098516 | 0.78 | BCHE (0.43) | LMNAGPR119BCHECCR1SLC18A3 | |
| SCHEMBL27622593 | 0.77 | NAMPT (0.40) | LMNAMAPTALDH1A1CCR1CYP3A4 | |
| SCHEMBL28059915 | 0.77 | CYP2C9 (0.51) | LMNAMAPTALDH1A1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105073730-A | monocyclic pyridine derivatives | WEI CAIR | 2015-11-18 | — | — | CN | disclosed |