Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17366255 | 0.82 | DRD4 (0.46) | SSTR4HPGDHTR2AHTR2BALDH1A1 | |
| SCHEMBL19962876 | 0.79 | ALDH1A1 (0.47) | SSTR4HPGDMEN1KMT2ATDP1 | |
| SCHEMBL20384325 | 0.79 | HTR2C (0.38) | RIPK1PDE4BHTR2AHTR2CHTR2B | |
| SCHEMBL4013290 | 0.79 | HTR2C (0.52) | HPGDMEN1KMT2AHTR2CHTR2B | |
| SCHEMBL2561303 | 0.79 | NOS3 (0.44) | HPGDRIPK1NOS3NOS1NOS2 | |
| SCHEMBL24334343 | 0.78 | KDM4E (0.54) | HPGDRIPK1NOS3NOS1NOS2 | |
| SCHEMBL22693816 | 0.78 | PDE4B (0.43) | HPGDRIPK1NOS3NOS1NOS2 | |
| SCHEMBL16852267 | 0.77 | PDE4B (0.43) | HPGDRIPK1PDE4BBRD4ALDH1A1 | |
| SCHEMBL12952643 | 0.76 | HPGD (0.52) | SSTR4HPGDALDH1A1 | |
| SCHEMBL20376109 | 0.76 | FFAR4 (0.43) | RIPK1HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588451-B1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INT (DE) | 2015-12-30 | — | — | EP | disclosed |