Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 6/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL17364190 | 0.99 | KDM4E (0.41) | CYP2C9CYP2C19CYP1A2CYP2D6MEN1 | |
| SCHEMBL18395010 | 0.84 | NR1H2 (0.43) | CYP2C9CYP2C19CYP1A2CYP2D6MEN1 | |
| Water SCHEMBL30689995 | 0.82 | NR1H2 (0.42) | CYP2C9CYP2C19CYP1A2CYP2D6MEN1 | |
| SCHEMBL2703373 | 0.82 | CYP2C9 (0.48) | CYP2C9CYP2C19CYP1A2CYP2D6CYP3A4 | |
| SCHEMBL8745144 | 0.81 | HDAC1 (0.47) | CYP2C9CYP2C19CYP1A2CYP2D6CYP3A4 | |
| SCHEMBL4630948 | 0.81 | CYP2C9 (0.47) | CYP2C9CYP2C19CYP1A2CYP2D6CYP3A4 | |
| SCHEMBL2704870 | 0.80 | CYP2C9 (0.49) | CYP2C9CYP2C19CYP1A2CYP2D6TP53 | |
| SCHEMBL8920560 | 0.79 | CYP2C9 (0.45) | CYP2C9CYP2C19CYP1A2CYP2D6CYP3A4 | |
| Formic Acid SCHEMBL18395650 | 0.79 | NR1H2 (0.40) | CYP2C9CYP2C19CYP1A2CYP2D6MEN1 | |
| SCHEMBL1228349 | 0.77 | CYP2C9 (0.58) | CYP2C9CYP2C19CYP1A2CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150374677-A1 | ANALOGS OF PRIDOPIDINE, THEIR PREPARATION AND USE | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2015-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150374677-A1 | ANALOGS OF PRIDOPIDINE, THEIR PREPARATION AND USE | QDPR, DRD2, OPRD1 | CYP2C9 75/4885CYP2C19 81/4885CYP1A2 156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.